Metformin-induced vitamin B12 deficiency: An underdiagnosed cause of diabetic neuropathy

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Jul 15, 2025 (publication date) through Jul 18, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jul 15, 2025; 16(7): 107514
Published online Jul 15, 2025. doi: 10.4239/wjd.v16.i7.107514

Figure 1 Folate and methionine cycles. BHMT: Betaine-homocysteine methyltransferase; SAM: S-adenosyl methionine; SAH: S-adenosyl homocysteine.

Citation: Alvarez M, Prieto AE, Portilla N, Moya D, Rincon O, Guzman I. Metformin-induced vitamin B12 deficiency: An underdiagnosed cause of diabetic neuropathy. World J Diabetes 2025; 16(7): 107514
URL: https://www.wjgnet.com/1948-9358/full/v16/i7/107514.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i7.107514