Altered hippocampal subfield volumes are associated with memory and executive function in patients with type 2 diabetes mellitus

Figure 1 Hippocampal subregion volumes with significant group differences and their correlations with cognitive scales. A: Significant differences in hippocampal subregion volumes between type 2 diabetes mellitus (T2DM) and healthy control groups; B and C: Hippocampal subregions in a coronal view of a patient with T2DM; D-H: Partial correlation coefficient of cognitive function with the right Hippocampus amygdala transition area volume in patients with T2DM; I: Partial correlation coefficient of cognitive function with the right molecular layer volume in patients with T2DM. ^aP < 0.05, ^bP < 0.01. T2DM: Type 2 diabetes mellitus; HC: Healthy control; TMT: Trail Making Test; DST: Digital Span Test; SDMT: Symbol Digit Modalities Test; AVLT: Auditory Verbal Learning Test; CA: Cornu ammonis; GC: Granular cell; DG: Dentate gyrus; HATA: Hippocampus amygdala transition area.