Single-nucleotide polymorphisms in genes involved in folate metabolism or selected other metabolites and risk for gestational diabetes mellitus

Figure 1 Two-site risk model of rs10830963 × rs4721. Light-colored grids represent the low-risk type, in which the positive score was less than the negative score. The dark-colored grids are the high-risk type, in which the positive score was greater than the negative score. CC × GT, CC × TT, and CG × GG were defined as low-risk types, and CC × GG, CG × GT, CG × TT, GG × GG, GG × GT, GG × TT were defined as high-risk types.