Reasons for discontinuing tirzepatide in randomized controlled trials: A systematic review and meta-analysis

Figure 1 Flowchart on study retrieval and inclusion in the meta-analysis.

Figure 2 Forest plot highlighting the proportion of study subjects with permanent discontinuation of the study drug in the tirzepatide vs placebo groups.

Figure 3 Forest plot highlighting the proportion of study subjects with permanent discontinuation of the study drug in the tirzepatide vs insulin groups.

Figure 4 Forest plot highlighting the proportion of study subjects with permanent discontinuation of the study drug in the tirzepatide vs glucagon-like peptide-1 receptor agonists groups. GLP-1RA: Glucagon-like peptide-1 receptor agonists.