Evaluation of teplizumab's efficacy and safety in treatment of type 1 diabetes mellitus: A systematic review and meta-analysis

Figure 1  Flow of selection of studies.

Figure 2 Assessment of risk of bias. A: Traffic light plot for assessment of risk of bias of included studies; B: Summary plot for assessment of risk of bias of included studies.

Figure 3  Funnel plot for assessment of publication bias of included studies.

Figure 4 Forest plot for positive outcomes. A: Reduction in insulin use; B: Change in C-peptide response; C: Change in glycated haemoglobin A1c level in Teplizumab versus control group. HbA1c: Glycated haemoglobin A1c; df: Degree of freedom; M-H: Mantel-Haenszel.

Figure 5 Forest plot for risk of adverse events in teplizumab vs control group. df: Degree of freedom; M-H: Mantel-Haenszel.

Figure 6  Box and Whisker plot for comparative Glycaemic control in Teplizumab vs control group.