Diabetes mellitus and prostate cancer risk: A mendelian randomization analysis

Figure 1 Selection of instrumental variables. A: Manhattan plot (line graph); B: Manhattan plot (cyclic graph). The red lines represent the filtering conditions of P < 5 × 10^-8.

Figure 2 Mendelian randomization analysis. A: Forest plot of three mendelian randomization methods; B: Scatter plot; C: Forest plot for each single nucleotide polymorphism. DM: Diabetes mellitus; MR: Mendelian randomization; SNP: Single nucleotide polymorphism.

Figure 3 Sensitivity analysis. A: Funnel plot; B: The result of leave-one-out method. DM: Diabetes mellitus; IV: Instrumental variable.