Multifaceted relationship between diabetes and kidney diseases: Beyond diabetes

Figure 1 Pure diabetic glomerulopathy. A: The glomerulus shows nodular expansion of the mesangial matrix and segmental sclerosis with hyalinosis (H&E 40 ×); B: Nodular mesangial matrix expansion with peripheralized capillaries (Jones methenamine silver 40 ×).

Figure 2 Nondiabetic kidney disease. A: Membranoproliferative glomerulonephritis and diabetic nephropathy. Lobulated glomerulus due to nodular mesangial expansion and endocapillary hypercellularity in a patient with diabetes and proliferative glomerulopathy with monoclonal immunoglobulin deposition (PAS 40 ×); B: Severe effacement of the foot processes over thickened glomerular basement membranes in a patient with diabetic glomerulosclerosis with superimposed podocyte injury (electron microscopy, magnification 2000 ×).