Clinical significance of serum miR-129-5p in patients with diabetes mellitus presenting macrovascular complications

Figure 1 The expression levels of serum miR-129-5p in healthy controls and in patients with diabetes mellitus and diabetic macrovascular complications. Data are presented as the mean ± SE. ^bP < 0.001, vs control. DM: Diabetes mellitus; DMCs: Diabetic macrovascular complications.

Figure 2 Receiver-operating characteristic curve analysis to analyze the potential of miR-129-5p as a serum marker for patients with diabetes mellitus or patients with diabetic macrovascular complications. A and B: Receiver-operating characteristic curves displaying sensitivity and specificity of serum miR-129-5p to diagnose patients with diabetes mellitus (A) or patients with diabetic macrovascular complications (B). Insets indicate the area under the curve values, 95% confidence intervals, and statistics. DM: Diabetes mellitus; DMCs: Diabetic macrovascular complications; AUC: Area under the curve; ROC: Receiver-operating characteristic.