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World J Diabetes. May 15, 2011; 2(5): 66-74
Published online May 15, 2011. doi: 10.4239/wjd.v2.i5.66
Published online May 15, 2011. doi: 10.4239/wjd.v2.i5.66
Nkx6.2 synergizes with Cdx-2 in stimulating proglucagon gene expression
Pei-Xiang Wang, Zhi-Wen Yu, Tian-Ru Jin, Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
Pei-Xiang Wang, Steven Wong, Tian-Ru Jin, Division of Cell and Molecular Biology, Toronto General Research Institute, University Health Network, M5G 1L7, Canada
Tian-Ru Jin, Department of Medicine, University of Toronto, Toronto, M5G 1L7, Canada
Author contributions: Wang PX performed the major experiments in Figure 1-4; Yu ZW performed mRNA extraction from cell lines and rat intestines. Wong S performed the NKX6 plasmid constructs; and Jin TR and Wang PX wrote the manuscript.
Supported by the Grants from the Canadian Institute of Health Research (CIHR, MOP36398) and Canadian Diabetes Association (1198) to Tianru Jin
Correspondence to: Tian-Ru Jin, PhD, Associate Professor, Department of Medicine and Department of Physiology, University of Toronto, Rm. 10-354, Toronto Medical Discovery Tower, the MaRS Building, 101 College St., Toronto, Ontario, Toronto, Ontario, M5G 1L7, Canada. tianru.jin@utoronto.ca
Telephone: +1-416-581-7670 Fax: +1-416-340-3453
Received: December 23, 2010
Revised: April 11, 2011
Accepted: April 18, 2011
Published online: May 15, 2011
Revised: April 11, 2011
Accepted: April 18, 2011
Published online: May 15, 2011
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