Tatiana L Karonova, MD, Professor, Department of endocrinology, Almazov National Medical Research Centre, Karonova, T (reprint author), Almazovs Ctr Heart Blood & Endocrinol, St Petersburg 197134, Russia., Russian Federation; Pavlov First Saint Petersburg State Medical University, Russian Federation; Pavlov First Saint Petersburg State Medical University, Russian Federation; Pavlov First Saint Petersburg State Medical University, Russian Federation; Pavlov First Saint Petersburg State Medical University, Russian Federation; Pavlov First Saint Petersburg State Medical University, 197341, Russia