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Nov 10, 2015 (publication date) through Jan 9, 2025
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World Journal of Diabetes
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1948-9358
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Irwin N, Flatt PR. New perspectives on exploitation of incretin peptides for the treatment of diabetes and related disorders. World J Diabetes 2015; 6(15): 1285-1295 [PMID: 26557956 DOI: 10.4239/wjd.v6.i15.1285] |
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| URL: | https://www.wjgnet.com/1948-9358/full/v6/i15/1285.htm |
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Di Zhang, Mingzhu Ma, Yueze Liu. Protective Effects of Incretin Against Age-Related Diseases. Current Drug Delivery 2019; 16(9): 793 doi: 10.2174/1567201816666191010145029
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| 2 |
Suzanne M. de la Monte. Insulin Resistance and Neurodegeneration: Progress Towards the Development of New Therapeutics for Alzheimer’s Disease. Drugs 2017; 77(1): 47 doi: 10.1007/s40265-016-0674-0
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S.L. Craig, R.A. Perry, S.S. Vyavahare, M.T. Ng, V.A Gault, P.R Flatt, N. Irwin. A GIP/xenin hybrid in combination with exendin-4 improves metabolic status in db/db diabetic mice and promotes enduring antidiabetic benefits in high fat fed mice. Biochemical Pharmacology 2020; 171: 113723 doi: 10.1016/j.bcp.2019.113723
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| 4 |
Angelica Artasensi, Alessandro Pedretti, Giulio Vistoli, Laura Fumagalli. Type 2 Diabetes Mellitus: A Review of Multi-Target Drugs. Molecules 2020; 25(8): 1987 doi: 10.3390/molecules25081987
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Shruti Mohan, R. Charlotte Moffett, Keith G. Thomas, Nigel Irwin, Peter R. Flatt. Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival. Biochimie 2019; 158: 191 doi: 10.1016/j.biochi.2019.01.008
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Carmen Gloria Aylwin H.. NUEVOS FÁRMACOS EN DIABETES MELLITUS. Revista Médica Clínica Las Condes 2016; 27(2): 235 doi: 10.1016/j.rmclc.2016.04.013
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| 7 |
Srividya Vasu, Mary K McGahon, R Charlotte Moffett, Tim M Curtis, J Michael Conlon, Yasser H A Abdel-Wahab, Peter R Flatt. Esculentin-2CHa(1–30) and its analogues: stability and mechanisms of insulinotropic action. Journal of Endocrinology 2017; 232(3): 423 doi: 10.1530/JOE-16-0453
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Patricio Atanes, Inmaculada Ruz-Maldonado, Shanta J. Persaud. Comprehensive Pharmacology. 2022; : 244 doi: 10.1016/B978-0-12-820472-6.00050-5
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Altaf Al-Romaiyan, Shanta J. Persaud, Peter M. Jones. Identification of Potential Plant-Derived Pancreatic Beta-Cell-Directed Agents Using New Custom-Designed Screening Method: Gymnema sylvestre as an Example. Molecules 2023; 29(1): 194 doi: 10.3390/molecules29010194
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| 10 |
Galyna V. Graham, J. Michael Conlon, Yasser H. Abdel-Wahab, Peter R. Flatt. Glucagon-like peptides-1 from phylogenetically ancient fish show potent anti-diabetic activities by acting as dual GLP1R and GCGR agonists. Molecular and Cellular Endocrinology 2019; 480: 54 doi: 10.1016/j.mce.2018.10.011
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| 11 |
Yanwei Li, Lin Li, Christian Hölscher. Incretin-based therapy for type 2 diabetes mellitus is promising for treating neurodegenerative diseases. Reviews in the Neurosciences 2016; 27(7): 689 doi: 10.1515/revneuro-2016-0018
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| 12 |
Ananyaa Sridhar, Dawood Khan, Peter R. Flatt, Charlotte R. Moffett, Nigel Irwin. GLP-1 receptor agonism and GIP receptor antagonism induce substantial alterations in enteroendocrine and islet cell populations in obese high fat fed mice. Peptides 2023; 169: 171093 doi: 10.1016/j.peptides.2023.171093
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| 13 |
Sarah L Craig, Nigel Irwin, Victor A Gault. Xenin and Related Peptides: Potential Therapeutic Role in Diabetes and Related Metabolic Disorders. Clinical Medicine Insights: Endocrinology and Diabetes 2021; 14 doi: 10.1177/11795514211043868
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| 14 |
Eko Fuji Ariyanto, Abdan Syakura Danil, Enny Rohmawaty, Budi Sujatmiko, Afiat Berbudi. Effect of Resveratrol in Melinjo Seed (Gnetum gnemon L.) Extract on Type
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| 15 |
F. P. M. O'Harte, M. T. Ng, A. M. Lynch, J. M. Conlon, P. R. Flatt. Dogfish glucagon analogues counter hyperglycaemia and enhance both insulin secretion and action in diet‐induced obese diabetic mice. Diabetes, Obesity and Metabolism 2016; 18(10): 1013 doi: 10.1111/dom.12713
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| 16 |
Ryan A. Lafferty, Peter R. Flatt, Nigel Irwin. Emerging therapeutic potential for peptide YY for obesity-diabetes. Peptides 2018; 100: 269 doi: 10.1016/j.peptides.2017.11.005
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| 17 |
Carlota Recio, Francesco Maione, Asif J. Iqbal, Nicola Mascolo, Vincenzo De Feo. The Potential Therapeutic Application of Peptides and Peptidomimetics in Cardiovascular Disease. Frontiers in Pharmacology 2017; 7 doi: 10.3389/fphar.2016.00526
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| 18 |
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| 19 |
S.L. Craig, V.A. Gault, S. McClean, G. Hamscher, N. Irwin. Effects of an enzymatically stable C-terminal hexapseudopeptide fragment peptide of xenin-25, ψ-xenin-6, on pancreatic islet function and metabolism. Molecular and Cellular Endocrinology 2019; 496: 110523 doi: 10.1016/j.mce.2019.110523
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| 20 |
Nigel Irwin, Victor A. Gault, Finbarr P.M. O’Harte, Peter R. Flatt. Blockade of gastric inhibitory polypeptide (GIP) action as a novel means of countering insulin resistance in the treatment of obesity-diabetes. Peptides 2020; 125: 170203 doi: 10.1016/j.peptides.2019.170203
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| 21 |
Yuka Kohda. Age-related hepatic glucose-dependent insulinotropic polypeptide expression is modified by ongoing thiamine supplementation in obese diabetic rats. Fundamental Toxicological Sciences 2020; 7(6): 291 doi: 10.2131/fts.7.291
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| 22 |
Pádraigín A. Harnedy-Rothwell, Chris M. McLaughlin, Aurélien V. Le Gouic, Ciaran Mullen, Vadivel Parthsarathy, Philip J. Allsopp, Emeir M. McSorley, Richard J. FitzGerald, Finbarr P. M. O’Harte. In Vitro and In Vivo Effects of Palmaria palmata Derived Peptides on Glucose Metabolism. International Journal of Peptide Research and Therapeutics 2021; 27(3): 1667 doi: 10.1007/s10989-021-10199-8
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| 23 |
Neil Tanday, Peter R. Flatt, Nigel Irwin. Metabolic responses and benefits of glucagon‐like peptide‐1 (GLP‐1) receptor ligands. British Journal of Pharmacology 2022; 179(4): 526 doi: 10.1111/bph.15485
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| 24 |
Dawood Khan, Charlotte R. Moffet, Peter R. Flatt, Catriona Kelly. Role of islet peptides in beta cell regulation and type 2 diabetes therapy. Peptides 2018; 100: 212 doi: 10.1016/j.peptides.2017.11.014
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| 25 |
Walter Ramsey, Carlos M. Isales. Understanding the Gut-Bone Signaling Axis. Advances in Experimental Medicine and Biology 2017; 1033: 13 doi: 10.1007/978-3-319-66653-2_2
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| 26 |
Namrata Prajapati, Dilip Sharma, Pankaj Ashok Bidve, Deepak Chouhan, Meghana Allani, Sagar kumar Patel, Moumita Ghosh Chowdhury, Amit Shard, Vinod Tiwari. Glucose regulation by newly synthesized boronic acid functionalized molecules as dipeptidyl peptidase IV inhibitor: a potential compound for therapeutic intervention in hyperglycaemia. Journal of Biomolecular Structure and Dynamics 2024; 42(6): 2859 doi: 10.1080/07391102.2023.2215319
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| 27 |
Aimee Coulter-Parkhill, Stephen McClean, Victor A Gault, Nigel Irwin. Therapeutic Potential of Peptides Derived from Animal Venoms: Current Views and Emerging Drugs for Diabetes. Clinical Medicine Insights: Endocrinology and Diabetes 2021; 14 doi: 10.1177/11795514211006071
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| 28 |
Brian M Moran, Aine M McKillop, Finbarr PM O’Harte. Development of novel ligands for peptide GPCRs. Current Opinion in Pharmacology 2016; 31: 57 doi: 10.1016/j.coph.2016.08.009
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| 29 |
S.L. Craig, V.A. Gault, C.E. Shiels, G. Hamscher, N. Irwin. Comparison of independent and combined effects of the neurotensin receptor agonist, JMV-449, and incretin mimetics on pancreatic islet function, glucose homeostasis and appetite control. Biochimica et Biophysica Acta (BBA) - General Subjects 2021; 1865(8): 129917 doi: 10.1016/j.bbagen.2021.129917
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| 30 |
IZ Qureshi, I Fatima. Peripherally administered KP-10 prevents development of insulin-induced hypoglycemic shock in diabetic rhesus monkeys. Physiology International 2020; 106(4): 335 doi: 10.1556/2060.106.2019.31
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| 31 |
Anand-Krishna Singh, Rameshwar Jatwa, Ashok Purohit, Heera Ram. Synthetic and phytocompounds based dipeptidyl peptidase-IV (DPP-IV) inhibitors for therapeutics of diabetes. Journal of Asian Natural Products Research 2017; 19(10): 1036 doi: 10.1080/10286020.2017.1307183
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| 32 |
Finbarr P. M. O’Harte, Vadivel Parthsarathy, Christopher Hogg, Peter R. Flatt, Christian Holscher. Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice. PLOS ONE 2018; 13(8): e0202350 doi: 10.1371/journal.pone.0202350
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| 33 |
Galyna V. Graham, Andrew McCloskey, Yasser H. Abdel-Wahab, J. Michael Conlon, Peter R. Flatt. A long-acting, dual-agonist analogue of lamprey GLP-1 shows potent insulinotropic, β-cell protective, and anorexic activities and improves glucose homeostasis in high fat-fed mice. Molecular and Cellular Endocrinology 2020; 499: 110584 doi: 10.1016/j.mce.2019.110584
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| 34 |
Clifford J. Rosen, Julie R. Ingelfinger. Shifting Tides Offer New Hope For Obesity. New England Journal of Medicine 2022; 387(3): 271 doi: 10.1056/NEJMe2206939
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| 35 |
Dipak Sarnobat, R. Charlotte Moffett, Victor A. Gault, Neil Tanday, Frank Reimann, Fiona M. Gribble, Peter R. Flatt, Nigel Irwin. Effects of long-acting GIP, xenin and oxyntomodulin peptide analogues on alpha-cell transdifferentiation in insulin-deficient diabetic GluCreERT2;ROSA26-eYFP mice. Peptides 2020; 125: 170205 doi: 10.1016/j.peptides.2019.170205
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| 36 |
Seunghun P. Lee, Jenson Qi, Guozhang Xu, Matthew M. Rankin, James Littrell, June Zhi Xu, Ivona Bakaj, Alessandro Pocai. GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action. Frontiers in Endocrinology 2021; 12 doi: 10.3389/fendo.2021.652628
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| 37 |
N.M. Pathak, V. Pathak, V.A. Gault, S. McClean, N. Irwin, P.R. Flatt. Novel dual incretin agonist peptide with antidiabetic and neuroprotective potential. Biochemical Pharmacology 2018; 155: 264 doi: 10.1016/j.bcp.2018.07.021
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| 38 |
Rachele A. Perry, Sarah. L. Craig, Victor A. Gault, Peter R. Flatt, Nigel Irwin. A novel neurotensin/xenin fusion peptide enhances β-cell function and exhibits antidiabetic efficacy in high-fat fed mice. Bioscience Reports 2021; 41(8) doi: 10.1042/BSR20211275
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| 39 |
Angelica Artasensi, Andrea Angeli, Carmen Lammi, Carlotta Bollati, Silvia Gervasoni, Giovanna Baron, Rosanna Matucci, Claudiu T. Supuran, Giulio Vistoli, Laura Fumagalli. Discovery of a Potent and Highly Selective Dipeptidyl Peptidase IV and Carbonic Anhydrase Inhibitor as “Antidiabesity” Agents Based on Repurposing and Morphing of WB-4101. Journal of Medicinal Chemistry 2022; 65(20): 13946 doi: 10.1021/acs.jmedchem.2c01192
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| 40 |
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| 41 |
Ryan A. Lafferty, Finbarr P. M. O’Harte, Nigel Irwin, Victor A. Gault, Peter R. Flatt. Proglucagon-Derived Peptides as Therapeutics. Frontiers in Endocrinology 2021; 12 doi: 10.3389/fendo.2021.689678
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| 42 |
Flavia Prodam, Simonetta Bellone, Roberta Ricotti, Alice Monzani, Giulia Genoni, Enza Giglione, Gianni Bona. Neonatology. 2018; : 535 doi: 10.1007/978-3-319-29489-6_184
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| 43 |
Srividya Vasu, Opeolu O. Ojo, R. Charlotte Moffett, J. Michael Conlon, Peter R. Flatt, Yasser H. A. Abdel-Wahab. Anti-diabetic actions of esculentin-2CHa(1–30) and its stable analogues in a diet-induced model of obesity-diabetes. Amino Acids 2017; 49(10): 1705 doi: 10.1007/s00726-017-2469-3
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| 44 |
Shruti Mohan, Peter R. Flatt, Nigel Irwin, R. Charlotte Moffett. Weight‐reducing, lipid‐lowering and antidiabetic activities of a novel arginine vasopressin analogue acting at the V1a and V1b receptors in high‐fat‐fed mice. Diabetes, Obesity and Metabolism 2021; 23(10): 2215 doi: 10.1111/dom.14462
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| 45 |
Asif Ali, Peter R Flatt, Nigel Irwin. Gut-Derived Peptide Hormone Analogues and Potential Treatment of Bone Disorders in Obesity and Diabetes Mellitus. Clinical Medicine Insights: Endocrinology and Diabetes 2024; 17 doi: 10.1177/11795514241238059
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