Laparoscopic resection of gastrointestinal stromal tumors: Does laparoscopic surgery provide an adequate oncologic resection?

Table 1 Review of case series

	All cases included		Study period 2000 onward		Follow-up 24+ mo
	LAP	OPEN	LAP	OPEN	LAP	OPEN
Total	1062	811	478	463	818	691
Conversion to OPEN	6.03% (64)	-	6.07% (29)	-	6.11% (50)	-
Complications	6.78% (72)	18.74% (152)	6.90% (33)	21.60% (100)	6.85% (56)	20.84% (144)
Mean/median size	2.7-6.1 cm1	3.15-9.2 cm	2.7-5.5 cm1	3.15-9.2 cm	2.7-6.1 cm1	3.15-9.2 cm
Follow-up	8-74 mo	18-91 mo	8-41 mo	21-91 mo	24-74 mo	36-91 mo
Margin positive	0.66% (7)	5.92% (48)	0.42% (2)	3.46% (16)	0.61% (6)	6.08% (42)
Recurrence	3.24% (31)2	7.16% (50)3	2.74% (11)4	4.80% (19)5	3.52% (25)6	7.61% (44)7
GIST-related mortality	0.85% (9)	3.33% (27)	0.42% (2)	0.86% (4)	0.86% (7)	3.91% (27)

¹Not including series of 4 patients and series where all tumors 2-5 cm (means not included);

²Out of 958 cases;

³Out of 698 cases;

⁴Out of 401 cases;

⁵Out of 396 cases;

⁶Out of 710 cases;

⁷Out of 578 cases. Summary of the experience of 32 independent case series: All the studies were observational studies reviewing outcomes of laparoscopic gastrointestinal stromal tumor resections, with or without a comparison group that had undergone open resection. This compilation amounted to 1873 cases, 1062 of which were laparoscopic[4,24,26,28,29,31-38,47-49,51-67]. LAP: Laparoscopic; OPEN: Open surgery.