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©The Author(s) 2017.
World J Gastrointest Endosc. Aug 16, 2017; 9(8): 405-410
Published online Aug 16, 2017. doi: 10.4253/wjge.v9.i8.405
Published online Aug 16, 2017. doi: 10.4253/wjge.v9.i8.405
Table 1 Demographic of mycophenolate mofetil treated patients and procedures (170 patients, 184 procedures) (%)
Characteristic | |
mean age | 57.05 |
Female | 89 (48.4) |
Indication for procedure2 | |
Screening | 72 (39.1) |
Diarrhea | 51 (27.7) |
Bleeding | 24 (13.0) |
Anemia | 20 (10.9) |
Abdominal pain | 14 (7.7) |
Constipation | 3 (1.6) |
Weight loss | 3 (1.6) |
Abnormal imaging | 3 (1.6) |
Bloating | 1 (0.52) |
Other (history of IBD, amyloid, stricture) | 9 (4.9) |
Indication for MMF | |
Organ transplant (kidney, liver, lung) | 116 |
Autoimmune | 35 |
Blood disorder | 7 |
Unknown indication | 26 |
Abnormal mucosa (gross) | 40 |
With normal biopsies | 10 |
With abnormal biopsies | 25 (2 duplicates) |
Without biopsies1 | 5 |
Normal mucosa (gross) | 144 |
With normal biopsies | 44 (normal biopsy or polypectomy, 1 for mass) |
With abnormal biopsies | 17 (1 duplicate) |
Without biopsies1 | 83 |
Table 2 Demographic of colitis among mycophenolate mofetil treated patients n (%)
Characteristic | |
n | 39 |
mean age | 51.44 |
Female | 20 (51.3) |
Indication for procedure | |
Diarrhea | 28 (71.8) |
Bleeding | 2 (5.1) |
Anemia | 1 (2.6) |
Screening | 4 (10.3) |
Abnormal imaging | 2 (5.1) |
Other (history of IBD) | 2 (5.1) |
Indication for MMF | |
Organ transplant | 28 (71.8) |
Autoimmune | 4 (10.3) |
Blood disorder | 7 (17.9) |
Table 3 Abnormal histological findings by mycophenolate mofetil indication
Solid organ transplant (n) | Autoimmune (n) | Blood disorder (n) | Total (n) | |
MMF colitis | 10 | 1 | 0 | 11 |
Graft vs host disease | 0 | 0 | 4 | 4 |
Nonspecific colitis | 11 | 0 | 1 | 12 |
Other | 3 (hyperplastic), 1 (lymphoid aggregate), 1 (kayexalate), 1 (ischemic), 1 (amyloid) | 1 (IBD), 1 (lymphoid aggregate), 1 (hyperplastic) | 1 (AML), 1 (reactive) | 12 |
- Citation: Izower MA, Rahman M, Molmenti EP, Bhaskaran MC, Amin VG, Khan S, Sultan K. Correlation of abnormal histology with endoscopic findings among mycophenolate mofetil treated patients. World J Gastrointest Endosc 2017; 9(8): 405-410
- URL: https://www.wjgnet.com/1948-5190/full/v9/i8/405.htm
- DOI: https://dx.doi.org/10.4253/wjge.v9.i8.405