Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified

Table 1 Demographics and clinical characteristics of the inflammatory bowel disease type unclassified patients

No. of patients, n (%)	36 (100)
Gender
Female	21 (58.3)
Male	15 (41.7)
Age (yr) (mean ± SD) at diagnosis	33.2 ± 13.1 (15-64)
Age (yr) (mean ± SD) at SBCE	35.9 ± 13.3 (18-64)
Device (no. patients), n (%)
PillCam® SB1	13 (36.1)
PillCam® SB2	16 (44.4)
PillCam® SB3	1 (2.8)
Mirocam®	5 (13.9)
Endocapsule®	1 (2.8)
Gastric transit time (min)	38.6 ± 44.7 (2–257)
Small bowel transit time (min)	290.4 ± 101.5 (52-480)
Incomplete SBCE	1 (2.8)
Capsule retention	0
Follow-up (mo) before SBCE	30.2 ± 29.9 (1-108)
Follow-up (mo) after SBCE	51.9 ± 40.5 (12-156)

IBDU: Inflammatory bowel disease type unclassified; SB: Small bowel; SBCE: Small bowel capsule endoscopy.

Table 2 Clinical characteristics and outcome of the patients with positive small bowel capsule

Case	Sex	Age	SBCE Findings	LS	Treatment pre-SBCE	Treatment post-SBCE	Diagnostic at follow-up
1	F	38	Multiple jejuno-ileal ulcerations	1404	5ASA	5 ASA + AZT	CD
2	F	18	Ulcer (n = 1) and edema of 3° tertile	143	AZT	Anti-TNF	CD
3	M	23	Ulcer (n = 1) and edema of 3° tertile	143	5ASA	5ASA	CD
4	F	20	Ulcerations (n = 2) and edema of 3° tertile	233	5ASA	5ASA	CD
5	F	33	Ulcer (n = 3) of 2° tertile	225	5ASA	5ASA	CD
6	F	19	Multiple ulcerations and edema of 3° tertile	908	5ASA	AZT	CD
7	M	60	Focal edema of 1° tertile	8	No treatment	5ASA	UC
8	M	22	Multiple jejuno-ileal ulcerations	2080	5ASA	5ASA + AZT	CD
9	F	32	Multiple ulcerations and edema of 3° tertile	908	5ASA	AZT	CD
10	F	27	Focal edema of 3° tertile	8	Prednisolone	anti-TNF	UC
11	F	47	Focal edema of 2° tertile	8	5ASA	5ASA	UC
12	F	31	Ulceration and edema of 1° (n = 5) and 2° tertile (n = 6)	879	5ASA+Prednisolone	AZT	CD
13	M	44	Focal edema of 3º tertile	8	5ASA	5ASA	UC

5ASA: Mesalamine; anti-TNF: Anti-tumor necrosis factor drug; AZT: Azathioprine; CD: Crohn’s disease; SBCE: Small bowel capsule endoscopy; LS: Lewis score; UC: Ulcerative colitis.

Table 3 Clinical characteristics and outcome of the patients with negative small bowel capsule

Case	Sex	Age	Treatment pre-SBCE	Treatment post-SBCE	Diagnostic at follow-up
1	M	45	5ASA	5ASA	IBDU
2	F	15	Prednisolone, 5ASA	5ASA	UC
3	F	27	AZT, 5ASA	AZT	UC
4	F	26	5ASA	5ASA	UC
5	M	31	5ASA	5ASA	IBDU
6	F	34	5ASA	5ASA	IBDU
7	M	21	5ASA	5ASA	IBDU
8	F	22	5ASA	5ASA, AZT	IBDU
9	F	56	5ASA	5ASA	UC
10	F	27	AZT, anti-TNF	AZT, anti-TNF	UC
11	F	30	5ASA	5ASA	UC
12	M	24	5ASA	5ASA	CD
13	M	49	5ASA	5ASA	UC
14	M	43	5ASA	5ASA	UC
15	F	30	5ASA + AZT	Anti-TNF	IBDU
16	M	24	5ASA	5ASA	UC
17	F	20	5ASA	5ASA	UC
18	M	55	5ASA	5ASA	IBDU
19	F	31	5ASA	5ASA, AZT, Anti-TNF	UC
20	F	48	5ASA	5ASA, AZT	IBDU
21	M	64	5ASA	5ASA	UC
22	M	44	No treatment	5ASA	IBDU
23	M	53	5ASA	5ASA	IBDU

5ASA: Mesalamine; anti-TNF: Anti-tumor necrosis factor drug; AZT: Azathioprine; CD: Crohn’s disease; IBDU: Colonic inflammatory bowel disease type unclassified; SBCE: Small bowel capsule endoscopy; UC: Ulcerative colitis.