Comparison of endoscopic stenting for malignant biliary obstruction: A single-center study

Table 1 Patients characteristics in the two groups

Variable	Single-step (n = 49)	Two-step (n = 41)	P
Mean age (yr)	70.1 ± 12.6	74.3 ± 9.9	NS
Gender (n)
Male	49	23	< 0.01
Female	0	18
Etiology of MBO:
pancratic cancer (%)	59.2	31.7	0.016
MPD tumor involvement present (%)	36.7	24.4	NS
Spincterotomy (%)	2.0	22.0	0.003
Hilar biliary obstruction (%)	22.4	46.3	0.03
Clinical stage
IVa > (%)	40.8	61	NS
IVb (%)	59.2	39	NS
Bilateral drainage (%)	4.1	12.2	NS
Technical success rate (%)	93.9	95.1	NS
Complication rate (%)	4.1	4.8	NS
Chemotherapy (%)	55.1	51.2	NS
Length of hospital stay (d)	28.1 ± 28.6	39.6 ± 25.7	< 0.05

MBO: Malignant biliary obstruction; MPD: Main pancreatic duct.

Table 2 Multivariate analysis to identify the clinical prognostic factors for patient survival

Variables	OR	95%CI	P
Step (single vs two)	0.81	0.49-1.36	0.42
Gender (male vs female)	1.05	0.66-1.67	0.83
Age (69 ≥vs 70 < )	1.02	0.59-1.76	0.96
Pancratic cancer (yes vs no)	1.01	0.21-1.61	0.98
Clinical stage (IVa ≥vs IVb)	2.03	1.23-3.34	0.006
Chemotherapy (with vs without)	2.18	1.27-3.76	0.005
Patency of the stent (no vs yes)	2.21	1.20-4.07	0.011