Prospective postsurgical capsule endoscopy in patients with Crohn’s disease

Table 1 Clinical characteristics of patients (n = 19)

Characteristics	Statistics
Age (yr)	37.6 ± 10.2
Gender (male/female)	14/5
Duration of CD (yr)	13.5 ± 10.6
Smoking (yes/no)	2/17
Disease location
Ileum only	4
Ileum and colon	15
Disease behavior (B1/B2/B3)	2/6/11
Surgical resection (times)
1	6
≥ 2	13
Type of surgery
Ileocolonic resection	16
Partial ileal resection	3
Ileostomy	7
Length of the residual small intestine (cm)	455 ± 52
Preoperative medications
Mesalamine	15
Elemental diet	12
Corticosteroids	6
Immunomodulators	1
Anti-TNFα antibody	4

Data are shown as the mean ± SD or number. Disease behavior was rated according to the Montreal classification: B1: Nonstricturing, nonpenetrating; B2: Stricturing; B3: Penetrating; TNF: Tumor necrosis factor; CD: Crohn’s disease.

Table 2 Changes in capsule endoscopy findings from shortly after surgery to 6-8 mo later

	CE shortly after surgery	CE 6-8 mo later	P value
Total LS	215:168 (8-562)	196:143 (8-450)	NS
Activity			NS
	No disease: 2	No disease: 4
	Mild disease: 11	Mild disease: 9
Edema LS
Proximal	40.6:8 (0-168)	36.3:8 (0-112)	NS
Mid	48:0 (0-280)	9.8:0 (0-112)	NS
Distal	31.4:0 (0-168)	27.1:0 (0-112)	NS
Ulcer LS
Proximal	10.4:0 (0-135)	41.5:0 (0-135)	NS
Mid	57.7:0 (0-300)	38.1:0 (0-225)	NS
Distal	133.8:135 (0-450)	118.8:0 (0-450)	NS
Aphthae/erosion (number)
Proximal	3.2:1 (0-12)	4.9:2 (0-17)	NS
Mid	2.1:2 (0-9)	10.5:3 (0-40)	0.036
Distal	1.6:1 (0-4)	8.1:5 (0-18)	0.015

Data are expressed as mean: median (range) or the number of patients. LS: Lewis score. Endoscopic disease activity: no disease (total LS < 135) and mild disease (135-790). NS: Not statistically significant; CE: Capsule endoscopy; CD: Crohn’s disease; LS: Lewis score.

Table 3 Comparison of postoperative endoscopic recurrence detection by ileocolonoscopy and capsule endoscopy in 6 patients who underwent ileocolonic resection

Cases	Ileocolonoscopy	Capsule endoscopy
	Rutgeerts score	Ulcer LS: 6-8 mo later (distal tertile)	A: Total LS shortly after surgery	B: Total LS: 6-8 mo later	ΔLS (B-A)
1	0	0	135	8	-127
2	1	135	278	135	-243
3	1	300	135	412	277 (recurrence)
4	2 (recurrence)	135	308	142	-166
5	2 (recurrence)	300	135	300	165 (recurrence)
6	2 (recurrence)	450	300	450	150 (recurrence)

ΔLS: Changes in total LS from shortly after surgery to 6-8 mo later. LS: Lewis score.