Brief Article
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastrointest Endosc. Aug 16, 2013; 5(8): 391-397
Published online Aug 16, 2013. doi: 10.4253/wjge.v5.i8.391
Table 1 Comorbidities of patients and indications for a colonoscopy for the complete cohort of patients
VariablePercentage95%CI
Comorbidities
Hypertension63.88%52.52-75.25
Diabetes44.44%32.68-56.20
Dyslipidemia22.22%12.38-32.06
Aspirin10.07%8.35-11.82
Chronic kidney disease5.55%0.10-11.00
Coronary artery disease4.16%0.10-9.00
Indication for colonoscopy
Bleeding per rectum22.94%21.50-24.38
Abdominal pain19.30%17.94-20.64
Surveillance16.29%15.03-17.55
Constipation9.57%8.57-10.58
Diarrhea8.75%7.79-9.72
Screening7.57%6.67-8.48
Weight loss5.50%4.72-6.28
Anemia5.02%4.27-5.76
Melena3.13%2.54-3.73
Anal pain1.91%1.45-2.38
Altered bowel habits1.76%1.31-2.21
Perianal fistula1.19%0.82-1.55
Positive for occult blood0.52%0.27-0.76
Table 2 Comorbidities of patients and indications for a colonoscopy stratified by the presence and absence of diverticulosis as well as the univariable analysis between the presence of diverticulosis and the corresponding variables
VariableDiverticulosisNo diverticulosisP-valueUnivariable analysis
OR95%CI
Comorbidities
Hypertension63.88%25.92%< 0.015.053.06-8.34
Diabetes44.44%24.32%< 0.012.491.53-4.05
Dyslipidemia22.22%10.77%0.032.371.31-4.27
Aspirin21.33%  9.23%0.012.671.48-4.81
Chronic kidney disease5.56%  3.12%0.382.910.82-10.29
Coronary artery disease4.16%  1.43%0.271.820.62-5.30
Indication for colonoscopy
Bleeding per rectum33.60% 22.08%< 0.011.791.35-2.35
Abdominal pain19.30% 15.20% 0.060.730.51-1.05
Constipation12.80%9.31% 0.111.430.96-2.11
Surveillance10.40% 16.72%< 0.010.580.38-0.87
Screening6.40% 7.67% 0.430.820.49-1.39
Anemia  6.00% 4.94% 0.51.230.71-2.12
Melena  3.13% 4.40% 0.311.470.78-2.79
Diarrhea  2.40% 9.28%< 0.010.240.11-0.55
Altered bowel habits   2.00% 1.74% 0.781.150.46-2.90
Weight loss  2.00% 5.79%< 0.010.330.14-0.82
Anal pain   1.20% 1.97% 0.290.60.19-1.94
Positive for occult blood  1.20% 0.46% 0.292.620.75-9.19
Perianal fistula    0.40%   1.25% 0.060.320.04-2.32
Table 3 Variables associated with the presence of diverticulosis on multivariable analysis
VariableMultivariable analysis
OR95%CI
Age1.051.03-1.07
Hypertension2.301.29-4.10
Bleeding per rectum2.571.50-4.38
Internal hemorrhoids1.961.06-3.65
Table 4 Factors associated with of bleeding per rectum in those with diverticulosis on univariable analysis, none of the variables were associated with bleeding per rectum on multivariable analysis
VariableOR95%CI
Age1.000.97-1.02
Hypertension0.730.27-1.95
Diabetes1.270.48-3.32
Dyslipidemia1.000.32-3.15
Atrial fibrillation0.440.05-3.50
Abdominal Pain0.190.07-0.57
Constipation0.750.33-1.70
Diarrhea0.390.04-3.38
Internal hemorrhoids2.611.48-4.61
Polyps1.280.72-2.29
Table 5 Findings on colonoscopy and possible etiologies for patients referred for bleeding per rectum
EtiologyPercentage95%CI
Internal hemorrhoids44.66%40.36-48.96
Diverticulosis33.60%27.73-39.47
Mass31.45%26.03-36.87
Polyps24.76%21.37-28.15
Colitis18.97%14.44-23.49