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Copyright ©2013 Baishideng Publishing Group Co.
World J Gastrointest Endosc. Feb 16, 2013; 5(2): 39-46
Published online Feb 16, 2013. doi: 10.4253/wjge.v5.i2.39
Table 1 Summary of American Society for Gastrointestinal Endoscopy, American Society of Colon and Rectal Surgeons, Society of American Gastrointestinal and Endoscopic Surgeons consensus recommendations on colon cleansing agents for bowel preparation during colonoscopy
AgentDosingRecommendationLevel of evidence
PEG240 mL every 10 min until rectal output is clear or total of 4 LFaster, more effective, better-tolerated compared to dietary restriction with cathartics, gut lavage, or mannitolGrade IA
Sulfate-free PEG240 mL every 10 min until rectal output is clear or total of 4 LBetter tasting, comparable to PEG in effectiveness and safety, acceptable alternative to PEGGrade IIB
Low-volume PEG/PEG-3350 and bisacodyl4 bisacodyl delayed-release tablets at noon, after bowel movement or 6 h, 240 mL every 10 min until 2 L is consumedEqually effective to standard 4-L PEG, better tolerated, acceptable alternative to 4-L PEGGrade IA
Aqueous sodium phosphateTwo doses of 30 to 45 mL sodium phosphate with 8 oz of liquid 10-12 h apartEqual alternative to PEG except for pediatric and elderly patients, bowel obstruction, renal failure, congestive heart and liver failureGrade IA
Sodium phosphate tablets20 tablets on the evening before the procedure, 12-20 tablets 3-5 h before the procedureImproved taste and palatability compared to aqueous sodium phosphate, but no improvement in patient toleranceGrade IA
Table 2 Predictive factors for quality of bowel preparation independent of colon cleansing agent
Patient-related factorsProcedure-related factors
Age > 65 yr
Male genderAdherence to bowel preparation instructions
Co-morbidityTiming of purgative administration
Diabetes
Stroke disease
Inpatient status
Low socioeconomic statusAppointment waiting times