Outcome in obscure gastrointestinal bleeding after capsule endoscopy

Table 1 Patients’ baseline characteristics

Characteristics	Overall	Occult-OGIB	Overt-OGIB	P value
Patients	100.00%	63.80%	36.20%	-
Age [yr, median (IQR)]	72 (5-79)	71 (5-78)	73 (49-82)	0.800
Gender (female)	45.70%	55.20%	28.90%	0.014
Bleeding-related drugs	41.90%	37.30%	50%	0.200
NSAIDs	30.50%	26.90%	36.80%	0.300
Hemoglobin level [g/dL, median (IQR)]	7.5 (6.4-9.3)	7.4 (6.0-9.1)	7.6 (6.5-9.4)	0.600
Transfusion requirements	61%	55.20%	71.10%	0.080
Transfusion requirements (blood units, mean ± SD)	2.01	1.7 ± 1.7	2.5 ± 2.3	0.037
Follow-up [d, median (IQR)]	326 (123-641)	330 (154-691)	217 (84-476)	0.500

NSAIDs: Non-steroidal anti-inflammatory drugs; OGIB: Obscure gastrointestinal bleeding; IQR: Interquartile range.

Table 2 Risk factors for rebleeding

Risk factors	Univariate Log-rank test	Multivariate
	P	HR	95%CI	P
Age > 70 yr	0.037	2.1	1.2-6.1	0.05
Gender	0.800	-	-	-
Overt OGIB presentation	0.130	-	-	-
Hb < 8.0 g/dL	0.027	2.7	1.9-6.3	0.03
Blood units transfused	0.180	-	-	-
Transfusions requirement	0.020	-	-	-
T ≥ 2 blood units	0.023	-	-	-
NSAID intake	0.900	-	-	-
Significant lesions in CE	0.036	2.4	1.1-5.8	0.01
Specific treatment carried out	0.500	-	-	-

OGIB: Obscure gastrointestinal bleeding; CE: Capsule endoscopy; NSAID: Non steroidal anti-inflammatory drugs; Hb: Hemoglobin; HR: Hazard ratios.