Brief Article
Copyright ©2010 Baishideng.
World J Gastrointest Endosc. Jan 16, 2010; 2(1): 36-40
Published online Jan 16, 2010. doi: 10.4253/wjge.v2.i1.36
Table 1 Gastric ulcer stages using a six-stage system[11]
StageFinding
A1 (active stage 1)Ulcer that contains mucus coating, with marginal elevation because of edema
A2 (active stage 2)Mucus-coated ulcer with discrete margin and less edema than active stage 1
H1 (healing stage 1)Unhealed ulcer covered by regenerating epithelium < 50%, with or without converging folds
H2 (healing stage 2)Ulcer with a mucosal break but almost covered with regenerating epithelium
S1 (scar stage 1)Red scar with rough epithelialization without mucosal break
S2 (scar stage 2)White scar with complete re-epithelialization
Table 2 Characteristics of patients and lesions
LafutidineRabeprazoleP
Gender (M:F)21:823:80.607
Age (mean ± SD)65.3 ± 8.065.4 ± 9.00.769
Body mass index (kg/m2) (mean ± SD)23.2 ± 3.123.0 ± 2.70.751
Anti-H. pylori antibody (positive:negative)23:624:70.729
Ulcerated lesion (yes:no)5:251:330.181
Location (upper:middle:lower)1:16:134:20:100.251
Lesion depth (mucosal layer: submucosal layer)27:333:10.677
Ulcer size immediately after ESD (mm) (mean ± SD)33.3 ± 9.234.7 ± 11.30.635
Table 3 Ulcer size reduction rate
LafutidineRabeprazoleP
Ulcer size (Day 0)33.3 ± 9.234.7 ± 11.30.635
Ulcer size (Day 28)10.5 ± 4.811.8 ± 6.70.421
Reduction rate32.30%33.50%0.974
Table 4 Distribution of ulcer stages on follow-up endoscopy 4 wk after ESD n (%)
StageLafutidineRabeprazole
A10 (0)0 (0)
A21 (3)1 (3)
H110 (33)11 (32)
H216 (54)19 (56)
S12 (7)3 (9)
S21 (3)0 (0)