Copyright
©The Author(s) 2024.
World J Gastrointest Endosc. Jun 16, 2024; 16(6): 326-334
Published online Jun 16, 2024. doi: 10.4253/wjge.v16.i6.326
Published online Jun 16, 2024. doi: 10.4253/wjge.v16.i6.326
Single UD (n = 137) | R0 resected UD (n = 79) | P value | |
Age, yr, mean (SD) | 54.75 ± 14.20 | 51.47 ± 12.31 | 0.088 |
Male sex | 70 (51.1) | 42 (53.2) | 0.779 |
Location of tumor | 0.563 | ||
Upper | 9 (6.6) | 4 (5.1) | |
Middle | 71 (51.8) | 47 (59.5) | |
Lower | 57 (41.6) | 28 (35.4) | |
Gross endoscopic appearance | 0.382 | ||
Elevated | 31 (22.6) | 12 (15.2) | |
Flat | 35 (25.6) | 20 (25.3) | |
Depressed | 71 (51.8) | 47 (59.5) | |
Tumor size, cm, mean (SD) | 2.04 ± 1.19 | 1.71 ± 1.06 | 0.266 |
≤ 2 cm | 73 (53.3) | 51 (64.6) | |
2.1-3 cm | 42 (30.7) | 19 (24.0) | |
> 3 cm | 22 (16.0) | 9 (11.4) | |
Depth of invasion | 0.043 | ||
M1 | 0 (0) | 0 (0) | |
M2 | 56 (40.9) | 40 (50.6) | |
M3 | 66 (48.2) | 39 (49.4) | |
SM1 | 4 (2.9) | 0 (0) | |
SM2 | 7 (5.1) | 0 (0) | |
SM3 | 4 (2.9) | 0 (0) | |
Histology | > 0.999 | ||
Poorly differentiated adenocarcinoma | 89 (65.0) | 51 (64.6) | |
Signet ring cell carcinoma | 48 (35.0) | 28 (35.4) | |
Enbolc resection | 127 (92.7) | 79 (100) | 0.060 |
Curative resection | 60 (43.8) | 51 (64.6) | 0.005 |
Non curative resection | 77 (56.2) | 28 (35.4) | |
Over 2 cm | 64 (46.7) | 28 (35.4) | 0.118 |
Submucosal invasion | 15 (10.9) | 0 (0) | 0.004 |
Positive lateral margin | 29 (21.1) | 0 (0) | < 0.001 |
Positive vertical margin | 9 (6.6) | 0 (0) | 0.028 |
Lymphovascular invasion | 5 (3.7) | 0 (0) | 0.274 |
R0 resection | 95 (69.3) | 79 (100) | < 0.001 |
Follow-up periods, months, mean (SD) | 68.83 ± 52.10 | 79.71 ± 45.42 | 0.123 |
Group A | Group B | P value | |
Less than 2 cm (n = 51) | Over 2 cm (n = 28) | ||
Age, yr, mean (SD) | 49.84 ± 11.90 | 54.43 ± 12.71 | 0.114 |
Male sex | 28 (54.9) | 14 (50) | 0.814 |
Location of tumor | 0.567 | ||
Upper | 3 (5.9) | 1 (3.6) | |
Middle | 28 (54.9) | 19 (67.8) | |
Lower | 20 (39.2) | 8 (28.6) | |
Gross endoscopic appearance | 0.148 | ||
Elevated | 10 (19.6) | 2 (7.1) | |
Flat | 10 (19.6) | 10 (35.7) | |
Depressed | 31 (60.8) | 16 (57.2) | |
Tumor size, cm, mean (SD) | 1.06 ± 0.60 | 2.89 ± 0.58 | < 0.001 |
≤ 2 cm | 51 (100) | 0 (0) | |
2.1-3 cm | 0 (0) | 19 (67.9) | |
> 3 cm | 0 (0) | 9 (32.1) | |
Depth of invasion | 0.062 | ||
M1 | 0 (0) | 0 (0) | |
M2 | 30 (58.8) | 10 (35.7) | |
M3 | 21 (41.2) | 18 (64.3) | |
Histology | 0.630 | ||
Poorly differentiated adenocarcinoma | 34 (66.7) | 17 (60.7) | |
Signet ring cell carcinoma | 17 (33.3) | 11 (39.3) | |
Follow-up periods, months, mean (SD) | 82.57 ± 43.62 | 74.51 ± 48.92 | 0.454 |
| Group A | Group B | P value |
Less than 2 cm (n = 51) | Over 2 cm (n = 28) | ||
Recurrence, n (%) | 1 (2) | 1 (3.6) | > 0.999 |
Local recurrence | 1 (2) | 1 (3.6) | |
Regional lymph node | 0 (0) | 0 (0) | |
Distant metastasis | 0 (0) | 0 (0) | |
Regional lymph node metastasis | 0 (0) | 0 (0) | |
Distant metastasis | 0 (0) | 0 (0) | |
Death | 0 (0) | 0 (0) | |
Recurrence free survival, months, mean (SD) | 204.12 ± 3.77 | 178.82 ± 9.03 | 0.7501 |
- Citation: Bae JY, Ryu CB, Lee MS, Dua KS. Long-term outcomes of endoscopic submucosal dissection for undifferentiated type early gastric cancer over 2 cm with R0 resection. World J Gastrointest Endosc 2024; 16(6): 326-334
- URL: https://www.wjgnet.com/1948-5190/full/v16/i6/326.htm
- DOI: https://dx.doi.org/10.4253/wjge.v16.i6.326