Endoscopic full-thickness plication along with argon plasma coagulation for treatment of proton pump inhibitor dependent gastroesophageal reflux disease

Table 1 Distribution of different baseline characteristics

Basic characteristics	No. of patients	Percentage
Age
≤ 20	2	8.7
21–30	8	34.8
31–40	5	21.7
41–50	4	17.4
51–60	1	4.3
61+	3	13.0
Gender
Female	8	34.8
Male	15	65.2
Hill’s classification
I	3	13.0
II	17	73.9
III	3	13.0
Manometry findings
Absent contractility	4	17.3
Fragmented peristalsis	1	4.3
Esophageal motility ineffective	12	52.2
Normal	6	26.1
Argon plasma coagulation
No	14	60.9
Yes	9	39.1
Number of clips
1	13	56.5
2	10	43.5
Complications
No complications	22	95.7
Hematemesis, dysphagia	1	4.3
Total	23	100

Table 2 Baseline patient characteristics mean and standard deviations

	n	Minimum	Maximum	Mean	SD
Age	23	17	73	36.78	15.53
Lower oesophageal sphincter pressure (mm Hg)	23	3.8	20.0	9.52	0
DeMeester score	23	7.90	129.00	48.32	34.59
Acid exposure time	23	5.00	39.30	15.03	10.47
Reflux episodes	23	21	332	88.61	68.91
Symptom index	23	0.0	100.0	60.11	29.30
Distal contractile integral	23	0.0	1732.0	456.40	510.54

Table 3 Comparison of gastroesophageal reflux disease health-related quality of life and symptom scores pre and post endoscopic full-thickness plication (EFTP; GERDx) procedure

Comparison of	Pre		Post		Wilcoxon signed rank test	P value
	Mean	SD	Mean	SD
Heartburn	17.96	10.38	3.52	5.18	3.91	0.001a
Regurgitation	18.26	6.66	2.04	3.38	4.20	0.001a
Total points	39.26	13.95	5.83	8.38	4.20	0.001a

^aP < 0.05, statistically significant.