Case Report
Copyright ©The Author(s) 2022.
World J Gastrointest Endosc. Jul 16, 2022; 14(7): 455-466
Published online Jul 16, 2022. doi: 10.4253/wjge.v14.i7.455
Table 1 Summary of the literature review of squamous cell lung carcinoma with pancreatic metastasis
Age in yr
Endoscopy +/- FNA
Diagnostic means
Overall survival
Status at time of publication
Zhou et al[29]2020China163MEpigastric pain with jaundiceHyperintense mass measuring 4.5 cm in the pancreatic headNoSurgery of the pancreatic massWhipple procedureUNKUNKUNK
Stoupis et al[30]2020Greece160FFatigue, cough and hemoptysis, loss of appetite and 10-kg weight lossIncreased 2-deoxy-2-[F-18] fluoro-D-glucose uptake in the right lung and pancreatic tailYesEUS-FNB of the pancreatic mass using a 22-gauge needle7 cycles of anti-PD-L1 antibody pembrolizumabUNKUNKAlive
Wang et al[4]2020China157MAsymptomaticPET-CT scan showed pancreatic metastasis (1 yr after diagnosis of squamous cell lung carcinoma)NoLaparoscopic radical pancreatic body tail and splenectomy4 cycles of gemcitabine (1000 mg/m2) plus cisplatin (65 mg/m2) due to progression of the lung mass and the appearance of a tumor in the head of the pancreas. He received 3 cycles of pembrolizumab (2 mg/kg)1 yr21.1 moDead
Ishikawa et al[31]2017Canada170MAbdominal pain and weight loss3.8 cm hypodense mass in the pancreatic body with lymphadenopathy in the left supraclavicular region and a 3-cm lung mass posterior to the left main stem bronchusYesEUS-FNB of these two lesions with a 25-G needlePalliative chemotherapyUNKUNKUNK
Fujji et al[32]2015Japan170MHigh fever and jaundice 6 mo after left lung inferior lobe resectionLow contrast-enhanced mass with relatively clear border and a size of 40 mm × 33 mm in the head of the pancreasYesFNA via a transgastric approach with linear EUS5 cycles of carboplatin plus weekly paclitaxel226 dUNKDead
Dewanwala et al[33]2012United States165MDyspnea and recurrent coughLeft hilar mass with an incidental well-defined mass involving the uncinate process of the pancreas measuring 3.7 cm × 2.2 cmYesPylorus-preserving pancreaticoduodenectomyCarboplatin plus gemcitabine and completed 5 cycles17 moUNKDead
Layfield et al[34]2010United States1UNKMUNKUNKYesEUS + FNA of the pancreatic massUNKUNKUNKUNK
Liratzopoulos et al[23]2006Greece153MJaundice, loss of appetite, nausea and mild abdominal painCT scan: carcinoma of the lower lobe of the right lung, a tumor in the pancreatic head measuring 4.0 cm × 4.1 cm × 3.5 cm, dilatation of the biliary tract and multiple enlarged lymph nodes in the cervical area, the mediastinum and the abdomenNoA percutaneous FNA of the pancreatic tumor under CT guidanceCholecystojejunostomy + dissection of lymph node near the pancreas19 dUNKDead
Mesa et al[35]2004United States2UNKUNKUNKMass in the head of the pancreas measuring 3.6 cm and a lung tumorYesEUS-FNA of the pancreatic massUNKUNKUNKUNK
Volkan et al[36]2004United States5 of 109 autopsy casesUNKUNKUNKUNKUNKAutopsyUNKUNKUNKDead
Tetsuya et al[37]2003Japan169MJaundiceLung tumor with hilar and mediastinal lymph node swelling and solitary pancreatic head tumor measuring 3 cmNoAutopsyEndoscopic nasobiliary drainage and stent drainage therapy prior to chemotherapy using gemcitabine4 moUNKDead
Moazzam et al[38]2002United States154MAnorexia, abdominal pain and jaundiceMass in right upper lung lobe and mass in the head of pancreasNoBiopsy of the right upper lobe lung massBiliary drainage + carboplatin and paclitaxelUNKUNKAlive: good clinical and radiographic response
Nakamura et al[11]2001Japan3 of 103 autopsy casesUNKUNKUNKUNKUNKAutopsyUNKUNKUNKDead
Matsukuma et al[39]1997Japan355MUNKUNKNoAutopsyUNKUNKUNKDead