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Copyright ©The Author(s) 2021.
World J Gastrointest Endosc. Dec 16, 2021; 13(12): 628-637
Published online Dec 16, 2021. doi: 10.4253/wjge.v13.i12.628
Table 1 Strengths and weaknesses of the different strategies for primary prophylaxis of variceal bleeding in cirrhosis
NSBBs
Carvedilol
EVL
Prevention of mortality++?+?
Prevention of bleeding++++
Prevention of other complications of cirrhosis++-
Reduction in HVPG+++-
Adverse effects-----
Serious adverse effects----
The plus sign (+) indicates strength. The minus sign (-) indicates weakness. The question mark (?) indicates uncertainty. NSBBs: Traditional non-selective beta-blockers; EVL: Endoscopic variceal ligation; HVPG: Hepatic venous pressure gradient.