Needle-based confocal endomicroscopy in the discrimination of mucinous from non-mucinous pancreatic cystic lesions

Table 1 Patients demographics and pancreatic cystic lesions features

Characteristic	Enrolled, n (%)
Patients, n	59
Age	64 ± 13
Sex, female	41 (70)
Clinical presentation
Asymptomatic	45 (76)
Abdominal pain	11 (19)
Pancreatitis	3 (5)
Site of lesion
Head	13 (22)
Uncinate process	8 (13)
Neck	6 (10)
Body	26 (45)
Tail	6 (10)
Cyst diameter mm	32 (22-45)
Morphology
Unilocular macrocyst	31 (52)
Multilocular microcyst	27 (46)
Microcyst	1 (2)
Main pancreatic duct diameter > 3 mm	5 (8)
Communication with a duct	1 (2)
Cyst wall diameter > 1 mm	20 (34)
Septa and/or wall nodules	35 (59)
CEA > 192 ng/mL	21 (35)
Amylases ≥ 50 UI/L	53 (90)

CEA: Carcinoembryonic antigen.

Table 2 Final diagnosis

Final diagnosis	n (%)
Serous cystoadenoma	13 (22)
Cystoadenocarcinoma	1 (2)
Branch-duct IPMN	34 (58)
Mucinous cystoadenoma	11 (18)

IPMN: Intraductal papillary mucinous neoplasm.

Table 3 Diagnostic yield of carcinoembryonic antigen and needle-based confocal laser endomicroscopy in mucinous vs non-mucinous lesions

	Sensitivity (%)	Specificity (%)	Accuracy (%)
CEA > 192 ng/mL	58.0	100.0	67.0
nCLE mucinous vs non-mucinous	80.0	100.0	84.0

CEA: Carcinoembryonic antigen; nCLE: Needle-based confocal laser endomicroscopy.