Copyright
©The Author(s) 2019.
World J Gastrointest Endosc. Feb 16, 2019; 11(2): 145-154
Published online Feb 16, 2019. doi: 10.4253/wjge.v11.i2.145
Published online Feb 16, 2019. doi: 10.4253/wjge.v11.i2.145
Table 1 Indications for upper endoscopy with duodenal biopsies and corresponding histopathology scores for each indication
Indication1 | Patients, n (%) | Histopathology, n (%) | ||
Normal | Atrophy | |||
Partial | Complete | |||
Dyspepsia | 47 (42.0) | 44 (93.6) | 2 (4.3) | 1 (2.1) |
Nausea or vomiting | 26 (23.2) | 25 (96.2) | 1 (3.8)2 | 0 |
Weight loss | 26 (23.2) | 19 (73.0) | 3 (11.5) | 4 (15.4) |
Iron-deficiency anemia | 16 (14.3) | 14 (87.5) | 1 (6.3) | 1 (6.3) |
Diarrhea | 15 (14.0) | 13 (86.7) | 0 | 2 (13.3) |
Rule out Celiac disease | 15 (14.0) | 13 (86.7) | 1 (6.7) | 1 (6.7) |
Follow up Celiac disease | 12 (10.7) | 4 (33.3) | 0 | 8 (66.7) |
Other3 | 3 (2.7) | 2 (66.7) | 1 (33.3) | 0 |
Total | 112 | 94 (84) | 12 (11) | 6 (5) |
Table 2 Agreement between narrow band imaging - based evaluation and histopathology scores
Histopathology1 | C-statistic | |||
Normal | Atrophy | |||
Performing endoscopist | Normal | 87 | 2 | 0.82 |
Atrophy | 7 | 16 | ||
Advanced endoscopist | Normal | 94 | 8 | 0.83 |
Atrophy | 0 | 10 | ||
GI Fellow | Normal | 76 | 0 | 0.86 |
Atrophy | 16 | 18 |
Table 3 Performance characteristics of narrow band imaging for distinguishing between normal mucosa and villous atrophy (partial or complete) as compared to histopathology
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | |
Performing endoscopist | 89 | 93 | 70 | 98 | 93 |
Advanced endoscopist | 56 | 100 | 100 | 93 | 93 |
Gastroenterology fellow | 100 | 83 | 53 | 100 | 86 |
Table 4 Interobserver agreement on narrow band imaging - based duodenal scoring
Performing endoscopist | Advanced endoscopist | GI Fellow | |
Performing endoscopist | - | - | - |
Advanced endoscopist | 0.55 | - | - |
GI Fellow | 0.65 | 0.371 | - |
- Citation: Tabibian JH, Perrault JF, Murray JA, Papadakis KA, Enders FT, Gostout CJ. Narrow band imaging evaluation of duodenal villi in patients with and without celiac disease: A prospective study. World J Gastrointest Endosc 2019; 11(2): 145-154
- URL: https://www.wjgnet.com/1948-5190/full/v11/i2/145.htm
- DOI: https://dx.doi.org/10.4253/wjge.v11.i2.145