Propofol vs traditional sedatives for sedation in endoscopy: A systematic review and meta-analysis

Figure 2 Propofol vs benzodiazepine associated with opioid - Forest plot of the meta-analysis. A: Comparing the occurrence of bradycardia between the propofol group and the benzodiazepine + opioid group (BZ + OP). Outcome: Bradycardia (defined as heart rate less than 50 bpm); B: Comparing the occurrence of oxygen desaturation between the propofol group and BZ + OP. Outcome: Hypotension (Defined as systolic blood pressure < 90 mmHg); C: Comparing the occurrence of desaturation between the propofol group and BZ + OP. Outcome: Oxygen desaturation (Defined as peripheral saturation of O₂ defined as < 90%); D: Comparing patient satisfaction with the sedation received for the procedure between the propofol group and BZ + OP. Outcome: Patient satisfaction (Visual analog scale – 0: very dissatisfied to 10: very satisfied); E: Comparing satisfaction of the endoscopists with the sedation administered for the procedure between the propofol group and BZ + OP. Outcome: Endoscopists satisfaction (Visual analog scale – 0: very dissatisfied to 10: very satisfied); F: Comparing patient recovery time after the procedure between the propofol group and BZ + OP. Outcome: Post procedure time to recovery (min).