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©2010 Baishideng.
World J Gastrointest Endosc. Aug 16, 2010; 2(8): 271-277
Published online Aug 16, 2010. doi: 10.4253/wjge.v2.i8.271
Published online Aug 16, 2010. doi: 10.4253/wjge.v2.i8.271
Figure 1 Diagnostic and therapeutic algorithm of gastrointestinal stromal tumor using endoscopic ultrasound-guided fine needle aspiration.
Quoted and modified from reference [8,14]. GIST: gastrointestinal stromal tumor; GI: gastrointestinal; SMT: submucosal tumor; EUS: endoscopic ultrasound; EUS-FNA: endoscopic ultrasound-guided fine needle aspiration.
Figure 2 Flow chart of diagnosis for gastrointestinal mesenchymal tumors using immunohistochemical analysis.
Quoted and modified from reference [16]. GIST: gastrointestinal stromal tumor; SMT: submucosal tumor.
Figure 3 Management process of gastric submucosal tumor (in a case of gastrointestinal stromal tumor) according to our institutional algorithm (Figure 1).
Quoted and modified from reference [15]. A: Esophagogastroduodenoscopy (EGD) shows submucosal tumor in the lower body of the stomach; B: Endoscopic ultrasound (EUS) reveals 2.5 cm subepithelial hypoechoic solid tumor with continuity to proper muscle layer (arrow-mp); C: Puncture of the small gastrointestinal stromal tumor (GIST) under EUS guidance. Arrow: tip of needle; D: The immunohistochemical fnding of endoscopic ultrasound-guided fne needle aspiration (EUS-FNA) specimen of GIST. The tumor is diffusely positive for c-kit.
Figure 4 Computed tomography at 2 years after surgery showing hepatic metastasis (arrow).
Quoted from reference [15].
Figure 5 Differential diagnosis of gastric submucosal tumor by endoscopic ultrasound.
Quoted and modified from reference [15]. GIST: gastrointestinal stromal tumor; SMT: submucosal tumor; EUS-FNA: endoscopic ultrasound-guided fine needle aspiration. 1Malignant tumor.
Figure 6 Management process of gastric submucosal tumor (in a case of ectopic pancreas) according to our institutional algorithm (Figure 2).
Quoted and modified from reference [15]. A: Esophagogastroduodenoscopy (EGD) showing submucosal tumor in the middle body of the stomach; B: Endoscopic ultrasound (EUS) revealing 1.5 cm subepithelial hypoechoic solid tumor with continuity to proper muscle layer (arrow-mp); C: Puncture of the small submucosal nodule under EUS guidance. Arrow: tip of needle; D: Histology of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) specimen reveals pancreatic acinar cells.
Figure 7 Management process of gastric submucosal tumor (in a case of B-cell lymphoma) according to our institutional algorithm (Figure 2).
Quoted and modified from reference [15]. A: Esophagogastroduodenoscopy (EGD) showing submucosal tumor in the middle body of the stomach; B; Endoscopic ultrasound (EUS) reveals 1.5 cm subepithelial hypoechoic solid tumor within submucosal layer. Proper muscle layer (arrow-mp) is intact; C: Puncture of the small gastric malignant lymphoma under EUS guidance. Arrow: tip of needle; D: The immunohistochemical findings of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) specimen reveals CD-20 positive diffuse large B cell lymphoma.
- Citation: Akahoshi K, Oya M. Gastrointestinal stromal tumor of the stomach: How to manage? World J Gastrointest Endosc 2010; 2(8): 271-277
- URL: https://www.wjgnet.com/1948-5190/full/v2/i8/271.htm
- DOI: https://dx.doi.org/10.4253/wjge.v2.i8.271