Endoscopic retrograde cholangiopancreatography in cirrhosis - a systematic review and meta-analysis focused on adverse events

Figure 1 Study selection process in accordance with preferred reporting items for systematic reviews and meta-analysis statement.

Figure 2 Forest plot. A: Incidence of ERCP-related hemorrhage = 4.58% (95%CI: 2.77-6.75%, P < 0.01, I² = 85.92%); B: Incidence of ERCP-related pancreatitis = 3.68% (95%CI: 1.83%-6.00%, P < 0.01, I² = 89.50%); C: Incidence of ERCP-related cholangitis = 1.93% (95%CI: 0.63%-3.71%, P < 0.01); D: Incidence of ERCP-related perforation = 0.00% (95%CI: 0.00%-0.23%, P = 0.08, I² = 37.8%); E: Meta-analysis of overall complications in six studies comparing cirrhosis and non-cirrhosis patients; F: Comparison of post-ERCP hemorrhage rates between cirrhosis and non-cirrhosis patients; G: Comparison of post-ERCP pancreatitis (PEP) rates between cirrhosis and non-cirrhosis patients; H: Comparison of post-ERCP cholangitis rates between cirrhosis and non-cirrhosis patients. ERCP: Endoscopic retrograde cholangiopancreatography.

Figure 3 Symmetrical funnel plot for the studies used in comparing overall complications to understand publication bias.