I am a self-starter who embraces new ideas and creates innovative methods for research of Gene Therapy. I have the leadership, training, expertise, and motivation necessary to successfully carry out rigorous scientific investigations. I have a broad background in medicine, molecular biology, and genetics, with specific training and expertise in gastroenterology, hepatology and gene therapy. I am treating a number of patients in the field and am an experienced physician. My research includes clinical trial of chemotherapy for cancers in the gastroenterology and hepatology field, and development of an efficient hydrodynamic gene delivery method and assess the utility and safety of its clinical application. To achieve this, I have combined the clinically well-established method of intravascular catheter insertion and developed a computer-controlled hydrodynamic gene delivery system. As a PI or co-Investigator on several Japanese federally-funded grants, I laid the groundwork for the proposed research by developing effective methods and analyzing efficacy and safety. Preclinical trials of this gene delivery method were assessed in large animal models, including dogs and pigs. In addition, I have successfully collaborated with other researchers to develop this gene delivery system to work towards this method being clinically approved. I have produced several peer-reviewed publications in the field. I am also aware of the importance of frequent communication among labstaff, students, and collaborators to move the projects forward and smoothly.