Systematic Reviews
Copyright ©The Author(s) 2017.
World J Hepatol. Feb 28, 2017; 9(6): 326-332
Published online Feb 28, 2017. doi: 10.4254/wjh.v9.i6.326
Table 1 Characteristics and outcomes of the included studies
Ref.YearDesign of the studySample sizeMean age (± SD)GenderMethod of diagnosis of sarcopeniaIndependent variableMethod of diagnosis of NAFLDFrequency of NAFLDResults of the studies
Hong et al[15]2014Cross-sectional45249.5 ± 10.3285 women (63.1%)DXASMI/weight (quartiles)CT (LAI)PrevalenceOR of having NAFLD by quartiles of SMI after adjusting for potential confounding factors: OR = 5.16 (95%CI: 1.63-16.33)
P = 0.041 after adjustment for age, sex, smoking status, phisical activity, HOMA-IR, hsCRP and 25[OH]D levels
Lee et al[16]2015Cross-sectional1513249.7 ± 16.59515 women (62.9%)DXASMI: < 32.2% for men and < 25.5% for womenHSI, CNS and LFS BARD and FIB-4 for advanced fibrosisPrevalence: 22%-29%Sarcopenic vs non-sarcopenic patients according to the NAFLD assessment method: OR = 1.18-1.22 (95%CI: 1.02-1.39)
P < 0.001 when adjusted for age, sex, regular exercise, HOMA-IR, smoking and HT
Moon et al[20]2013Cross-sectional956547 ± 10.35293 men (55.3%)BIA multi frequenciesSVR (quartiles)Surrogate marker: FLI ≥ 60Prevalence: 19.32%OR for NAFLD among the quartiles of SVR using multiple logistic regression analysis: OR = 0.037 (95%CI: 0.029-0.049)
P < 0.001 when adjusted for age, sex, total cholesterol, low-density lipoprotein cholesterol, DM, HTN, hsCRP