Primary biliary cholangitis metachronously complicated with combined hepatocellular carcinoma-cholangiocellular carcinoma and hepatocellular carcinoma

Table 1 Laboratory data on the initial hepatectomy

WBC	5800/μL	ALP	228 U/L	PIVKA-II	18 mAU/mL
RBC	432 × 104/μL	γ-GTP	65 U/L	AFP	3 ng/mL
Hb	13.0 g/dL	ChE	280 IU/L	AFP-L3	0.5%
Ht	38%	BUN	14.5 mg/dL	CEA	1.2 ng/mL
Plt	22.6 × 104/μL	Cr	0.54 mg/dL	CA 19-9	7 U/mL
PT	77.3%	T-Chol	203 mg/dL	ANA	× 40
PT-INR	1.04	TG	77 mg/dL	AMA	× 640
TP	7.9 g/dL	ICG-R15	8.3%	AMA-M2	158 Index
Alb	4.2 g/dL	Glucose	109 mg/dL	HBs Ag	(-)
TBil	0.5 mg/dL	CRP	0.2 mg/dL	HBs Ab	(-)
AST	19 U/L	IgG	1760 mg/dL	HBc Ab	(-)
ALT	14 U/L	IgM	305 mg/dL	HCV Ab	(-)
LDH	183 U/L

AFP: Alpha-fetoprotein; AFP-L3: A Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein; Alb: Albumin; ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AMA: Antimitochondrial antibody; AMA-M2: Anti-mitochondrial M2 antibody; ANA: Antinuclear antibodies; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; CA 19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; ChE: Cholinesterase; Cr: Creatinine; CRP: C-reactive protein; γ-GTP: Gamma-glutamyltransferase; Hb: Hemoglobin; HBcAb: Hepatitis B core antibody; HBsAb: Hepatitis B surface antibody; HBsAg: Hepatitis B virus antigen; HCVAb: Hepatitis C virus antibody; Ht: Hematocrit; ICG-R15: 15-min retention rates of indocyanine green test; IgG: Immune globulin G; IgM: Immune globulin M; LDH: Lactate dehydrogenase; PIVKA-II: Prothrombin-induced vitamin K absence II; Plt: Platelet; PT: Prothrombin time; PT-INR: Prothrombin time international normalized ratio; RBC: Red blood cell count; TBil: Total bilirubin; T-Chol: Total cholesterol; TG: Triglyceride; TP: Total protein; WBC: White blood cell count.

Table 2 Laboratory data on the re-hepatectomy

WBC	3600/μL	AST	29 U/L	PIVKA-II	28 mAU/mL
RBC	397 × 104/μL	ALT	18 U/L	AFP	5 ng/mL
Hb	12.0 g/dL	LDH	186 U/L	AFP-L3	11.7%
Ht	35.9%	ALP	300 U/L	CEA	1.0 ng/mL
Plt	22.3 × 104/μL	γ-GTP	79 U/L	CA 19-9	29 U/mL
PT	77.3%	ChE	211 IU/L	ICG-R15	7.4%
PT-INR	1.12	BUN	16.1 mg/dL	Glucose	138 mg/dL
TP	7.3 g/dL	Cr	0.6 mg/dL	CRP	0.2 mg/dL
Alb	3.8 g/dL	T-Bil	0.4 mg/dL

AFP: Alpha-fetoprotein; AFP-L3: A Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein; Alb: Albumin; ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; ChE: Cholinesterase; Cr: Creatinine; CRP: C-reactive protein; γ-GTP: Gamma-glutamyltransferase; Hb: Hemoglobin; Ht: Hematocrit; ICG-R15: 15-min retention rates of indocyanine green test; LDH: Lactate dehydrogenase; PIVKA-II: Prothrombin-induced vitamin K absence II; Plt: Platelet; PT: Prothrombin time; PT-INR: Prothrombin time international normalized ratio; RBC: Red blood cell count; T.Bil: Total bilirubin; TP: Total protein; WBC: White blood cell count.