Hepatitis C virus genotypes in north eastern Algeria: A retrospective study

Table 1 Distribution of study population n (%)

Variables	Total	Sex		P value
		Male, 150 (34.5)	Female, 285 (65.5)
Age (yr)	20-29	12 (8)	7 (2.5)	0.04
	30-39	13 (8.7)	20 (7)
	40-49	28 (18.7)	48 (16.8)
	50-59	50 (33.3)	128 (44.9)
	60-69	33 (22)	63 (22.1)
	> 70	14 (9.3)	19 (6.7)
Region	Central	112 (74.66)	247 (86.66)	0.002
	North	31 (20.66)	26 (9.12)
	South	7 (4.66)	12 (4.21)

Table 2 Hepatitis C virus genotypes in eastern Algerian population

Genotype	n (%)	Subtype	n (%)
1	386 (88.7)	1a	6 (1.55)
		1a/1b	1 (0.26)
		1b	375 (97.2)
		Undefined subtypes	4 (1.0)
2	37 (8.5)	2a/2c	18 (48.6)
		2a	1 (2.7)
		2b	2 (5.4)
		Undefined subtypes	16 (43.2)
3	4 (0.9)	3a	4 (100)
4	5 (1.1)	4a	1 (20)
		4a/4c/4d	1 (20)
		Undefined subtypes	3 (60)
5	1 (0.2)	5a	1 (100)
Unclassified	2 (0.4)		2 (100)

Table 3 Hepatitis C virus genotypes according to age, sex, region and viral load n (%)

Risk factors	Genotype 1	Other genotypes	P value
Age (yr)			< 0.0001
< 60	284 (65.3)	22 (5.1)
≥ 60	102 (23.4)	27 (6.2)
Sex			0.8
Male	132 (30.3)	18 (4.1)
Female	254 (58.4)	31 (7.1)
Region			< 0.01
Central	327 (75.2)	32 (7.4)
North	43 (9.9)	14 (3.2)
South	16 (3.7)	3 (0.7)
Viral load (IU/mL)			0.2
< 600000	144 (33.1)	15 (3.4)
≥ 600000	241 (55.4)	33 (7.6)

Table 4 Relationship between hepatitis C virus genotype and age

Age group (yr)	n	Genotype 1	Crude OR (95%CI)	Adjusted OR by region (95%CI)	InteractionAge × region
< 60	306	92.8%	0.30b (0.2-0.5)	0.20b (0.1-0.5)	No
≥ 60	129	79.1%

^bP < 0.001 vs genotype 1.