In vivo assessment of intratumoral aspirin injection to treat hepatic tumors

Table 1 Mean percentage values of remaining tumor area 24 h after treatment

Analysis	Groups		P value
	Group 1 (control)	Group 2 (aspirin)
mean ± SD	98.5% ± 1.512%	8.5% ± 0.707%	0.0036
Median	98.5%	0%
25 percentile	97.75%	0%
75 percentile	100%	2%

Table 2 Mean serum alkaline phosphatase levels at three times (D0, D4 and D11)

Variables	Times
	Tumor implant (D0)	Day of treatment (D4)	7 d after treatment (D11)
Group 3 control - AP (U/L)	1341	1292	1723
Group 4 aspirin - AP (U/L)	1281	1392	1173
DMS value	15.3	14.6	19.5
CV value	9.39	8.69	11.7
F test value	0.63 (NS)	1.51 (NS)	31.94

^1,2No difference between them (DMS) at 5% significance level;

³Difference between them (DMS) at 5% significance level;

⁴Statistically significant. NS: Not significant; AP: Alkaline phosphatase; CV: Coefficient of variation; DMS: Tukey test.

Table 3 Mean percentage values of remaining tumor area 7 d after treatment

Analysis	Groups		P value
	Group 3 (control)	Group 4 (aspirin)
mean ± SD	94% ± 2.726%	11% ± 4.243%	0.0035
Median	94.5%	0%
25 percentile	91.75%	0%
75 percentile	96.25%	2%