Occult hepatitis B virus infection among Egyptian blood donors

Table 1 Hepatitis B virus markers among 280 antibodies to hepatitis B core positive blood donors

Anti-HBc positive donors n (%)	Anti-HBc Architec	Anti-HBs	HBV-DNA
102 (36.4)	+ve	-ve	-ve
29 (10.4)	+ve	-ve	+ve
97 (34.6)	+ve	+ve	-ve
16 (5.7)	+ve	+ve	+ve
24 (8.6)	-ve	-ve	-ve
10 (3.6)	-ve	+ve	-ve
2 (0.7)	-ve	-ve	+ve

Anti-HBc: Antibodies to hepatitis B core; Anti-HBs: Antibodies to hepatitis B surface; HBV: Hepatitis B virus.

Table 2 Age as a risk factor for antibodies to hepatitis B core and hepatitis B virus DNA positivity among blood donors

Risk factor	n (%)	Crude odds ratio (95%CI)	Adjusted odds ratioΩAOR (95%CI)
For anti-HBc +ve
Age > 30 yr	196/853 (23.0)	2.1 (1.7-2.7)b	1.8 (1.4-2.4)b
Age ≤ 30 yr	151/1233 (12.2)	®	®
Marital status
Married	287/1530 (18.8)	2 (1.5-2.5)b	1.4 (1.0-1.9)
Single	94/898 (10.5)	®	®
For HBV-DNA+ve
Age ≤ 30 yr	29/95 (30.5)	3.6 (1.7-7.4)b	3.8 (1.8-7.9)b
Age > 30 yr	13/119 (10.9)	®

Table 3 Hepatitis B virus markers among antibodies to hepatitis B core positive blood donors in relation to hepatitis B virus DNA concentration n (%)

Variable	HBV-DNA≥200	HBV-DNA < 200	P value
	(n = 27)	(n = 26)
Age (mean ± SD)	29.1 ± 6.7	29.2 ± 7.1	0.972
Gender
Males	26 (57.8)	19 (42.2)	0.088
Females	1 (16.7)	5 (83.3)
Marital status
Single	7 (50.0)	7 (50.0)	0.75
Married	16 (55.2)	13 (44.8)
Donation site
Ain Shams Hospital	27 (54.0)	23 (46.0)	0.11
Central blood bank	0 (0.0)	3 (100.0)
Previous blood donation	16 (64.0)	9 (36.0)	0.12
ALT (mean ± SD)	33.2 ± 14.7	34.4 ± 17.6	0.868
AST (mean ± SD)	25.5 ± 13.5	26.1 ± 10.8	0.671
Anti-HBs (mean ± SD)	156.1 ± 359.3	59.9 ± 203.8	0.634
Architect HBV
+ve	23 (51.1)	22 (48.9)	0.99
-ve	2 (66.7)	1 (33.3)
Anti-HBs level
< 10	18 (51.4)	17 (48.6)	0.447
10-	5 (50.0)	5 (50.0)
100-	0 (0.0)	1 (100)
≥ 1000	4 (80.0)	1 (20.0)

ALT: Alanine aminotransferase; AST: Aspartate transaminase; Anti-HBs: Antibodies to hepatitis B surface; HBV: Hepatitis B virus.