Liver function linked to bone health: A bibliometric of the liver-bone axis

Table 1 Main information about data

Description	Results
Documents	855
Annual growth rate	3.43%
Document average age	35.63
Citations	27485
Average citations per document	32.15
Journals (Sources)	365
References	18858
Average references per document	22.06
Journals (References)	4046
Article	694
Review	161
Authors	4988
Co-authors per document	5.83
International co-authorships	15.91%
Countries	61
Institutions	425

Table 2 The top 10 countries in the bone-liver axis

Rank	Publications, n (%)	Centrality	Country	Citation	AC
1	214 (25.03)	0.53	United States	10836	50.64
2	168 (19.65)	0.05	China	2875	17.11
3	61 (7.13)	0	Japan	1607	26.34
4	60 (7.02)	0.25	Italy	2745	45.75
5	58 (6.78)	0.2	Spain	2119	36.53
6	49 (5.73)	0.34	Germany	1988	40.57
7	41 (4.80)	0.13	United Kingdom	2588	63.12
8	39 (4.56)	0	South Korea	891	22.85
9	26 (3.04)	0.05	Brazil	494	19.00
10	20 (2.34)	0.32	Sweden	881	44.05

AC: Average citation.

Table 3 The top 10 institutions in terms of centrality

Rank	Publications	Centrality	Institution	Country
1	22	0.21	University of California System	United States
2	5	0.21	David Geffen School of Medicine at University of California, Los Angeles	United States
3	11	0.19	Icahn School of Medicine at Mount Sinai	United States
4	8	0.15	Jackson Laboratory	United States
5	9	0.12	Beth Israel Deaconess Medical Center	United States
6	5	0.09	Boston University	United States
7	15	0.06	Shanghai Jiao Tong University	China
8	3	0.05	CIBEROBN	Spain
9	20	0.04	Mayo Clinic	United States
10	16	0.04	CIBER - Centro de Investigacion Biomedica en Red	Spain

Table 4 The top 10 authors in terms of number of publications

Rank	Author	Count	H-index	Citation	HCSA	AC	Country
1	Guanabens N	18	36	877	119	48.72	Spain
2	Albert P	14	61	721	119	51.50	Spain
3	Rosen CJ	14	99	1178	737	84.14	United States
4	Pilar P	13	32	772	123	59.38	Spain
5	Ana M	10	34	528	123	52.80	Spain
6	Emilio GR	10	26	194	60	19.40	United States
7	J. Eileen H	8	36	526	138	65.75	United States
8	Keith D L	8	94	387	128	48.38	Belgium
9	Shoshana Y	8	40	325	84	40.63	United States
10	Francisco SF	8	19	155	60	19.38	United States

HCSA: Highest citation single article; AC: Average citation.

Table 5 The top 10 journals in terms of number of publications

Rank	Journal	Count, n(%)	Citation	AC	IF (2023)	JCR (2024)	Country
1	Osteoporosis International	28 (3.27)	800	28.57	4.2	Q1	United Kingdom
2	Journal of Bone and Mineral Research	20 (2.34)	771	38.55	5.1	Q1	United States
3	Frontiers in Endocrinology	18 (2.11)	293	16.28	3.9	Q2	United States
4	World Journal of Gastroenterology	18 (2.11)	592	32.89	4.3	Q1	United States
5	Transplantation Proceedings	17 (1.99)	156	9.18	0.8	Q4	United States
6	Journal of Hepatology	16 (1.87)	993	62.06	26.8	Q1	Netherlands
7	Journal of Clinical Endocrinology and Metabolism	15 (1.75)	535	35.67	5.0	Q1	United States
8	Plos One	15 (1.75)	445	29.67	2.9	Q1	United States
9	Calcified Tissue International	14 (1.64)	800	57.14	3.3	Q2	United States
10	Liver Transplantation	14 (1.64)	368	26.29	4.7	Q1	United States

AC: Average citation; IF: Impact factor; JCR: Journal citation reports.

Table 6 The top 10 co-citation references

Rank	Title	First author	Source	Citations	TLS	Year	Type
1	Bone mineral density, serum insulin-like growth factor I, and bone turnover markers in viral cirrhosis	Gallego-Rojo FJ	Hepatology	96	787	1998	Article
2	Rates of vertebral bone loss before and after liver-transplantation in women with primary biliary-cirrhosis	Eastell R	Hepatology	74	638	1991	Article
3	AGA Technical Review on osteoporosis in hepatic disorders	Leslie WD	Gastroenterology	74	576	2003	Review
4	Osteoporosis and bone mineral metabolism disorders in cirrhotic patients referred for orthotopic liver transplantation	Monegal A	Calcified Tissue International	69	610	1997	Article
5	Bone disorders in chronic liver disease	Collier J	Hepatology	65	484	2007	Review
6	Role of hyperbilirubinemia in the impairment of osteoblast proliferation-associated with cholestatic jaundice	Janes CH	Journal of Clinical Investigation	63	580	1995	Article
7	Bone mineral density before and after OLT: Long-term follow-up and predictive factors	Guichelaar MMJ	Liver Transplantation	61	548	2006	Article
8	Reduced bone mineral density and altered bone turnover markers in patients with non-cirrhotic chronic hepatitis B or C infection	Schiefke I	World Journal of Gastroenterology	59	423	2005	Article
9	Osteoporosis and skeletal fractures in chronic liver-disease	Diamond T	Gut	58	508	1990	Article
10	Association of nonalcoholic fatty liver disease with low bone mass in postmenopausal women	Moon SS	Endocrine	57	299	2012	Article

TLS: Total link strength.

Table 7 The top 20 most occurring keywords

Rank	Keyword	Occurrences
1	Osteoporosis	373
2	Bone mineral density	151
3	Disease	132
4	Mineral density	120
5	Primary biliary-cirrhosis	97
6	Metabolism	85
7	Postmenopausal women	76
8	Risk	76
9	Cirrhosis	74
10	Insulin-resistance	68
11	Osteopenia	65
12	Women	63
13	Expression	61
14	Bone	59
15	Hepatic osteodystrophy	59
16	Fractures	58
17	Liver	58
18	Mass	55
19	Vitamin-D	55
20	Obesity	52