Observational Study
Copyright ©The Author(s) 2024.
World J Hepatol. Jun 27, 2024; 16(6): 912-919
Published online Jun 27, 2024. doi: 10.4254/wjh.v16.i6.912
Table 1 Baseline characteristics of coronavirus disease 2019 hospitalizations in non-alcoholic fatty liver disease patients with different levels of obesity: Insights from national inpatient sample 2020
Variables

Overweight, %
Class I, %
Class II, %
Class III, %
P value
Age (yr) at admission    Mean58535248< 0.001
Sex    Male58.559.75243.3< 0.001
    Female41.540.34856.7< 0.001
Race    White42.141.64549.5< 0.001
    Black7.911.814.915.8< 0.001
    Hispanic43.841.436.330.9< 0.001
    Asian/PI5.14.51.82.2< 0.001
    Nat. American< 0.10.821.6< 0.001
Payer    Medicare34.126.426.619.9< 0.001
    Medicaid26.721.815.120.7< 0.001
    Private3344.849.150.9< 0.001
    Self-pay5.16.78.78.1< 0.001
Admission type    Non-elective9998.898.497.7< 0.001
Comorbidities     Hypertension61.156.458.459.10.024
    Diabetes46.646.748.850.6< 0.001
    Hyperlipidemia45.142.541.632.3< 0.001
    PVD3.13.65.32.2< 0.001
    Tobacco use disorder19.221.620.317.6< 0.001
    Prior MI3.121.61.60.007
    Prior TIA/Stroke3.12.831.7< 0.001
    Prior VTE2.643.64.20.090
    Cancer5.22.51.72.5< 0.001
    CKD11.49.19.98.70.029
    Drug abuse2.11.21.71.80.161
    Cannabis use disorder< 0.10.80.60.90.029
    Depression7.310.111.413.1< 0.001
    Chronic pulmonary disease15.518.321.426.1< 0.001
    Hypothyroidism10.99.110.513.9< 0.001
    Bariatric surgery< 0.10.91.91.5< 0.001
Discharge     Routine66.777.478.977.3< 0.001
    Transfer to short term< 0.1322< 0.001
    Hospital
    Other: SNF, ICF, etc.16.76.97.59%< 0.001
    Home health care15.512.711.611.7< 0.001
Length of stay (d)    Median10888< 0.001
Table 2 Multivariable odds of in-hospital outcomes in obese coronavirus disease 2019 hospitalizations with non-alcoholic fatty liver disease
Obesity II vs IObesity III vs IObesity I vs overweight
OutcomesaOR [LL-UL]aOR [LL-UL]aOR [LL-UL]P value
MACCE1.19 [0.78-1.81]1.82 [1.22-2.73]1.66 [0.92-2.98]0.016
Death during hospitalization1.10 [0.69-1.76]1.96 [1.23-3.11]1.59 [0.84-3.02]0.015
Acute myocardial infarction1.91 [0.77-4.72]2.32 [0.92-5.88]1.72 [0.53-5.57]0.346
Cardiac arrest1.14 [0.49-2.67]1.25 [0.56-2.80]0.60 [0.13-2.78]0.782
Acute ischemic stroke0.23 [0.04-1.28]0.36 [0.06-2.02]5.52 [0.55-55.56]0.130
Respiratory failure1.27 [0.99-1.61]1.35 [1.07-1.70]0.97 [0.67-1.41]0.049
Mechanical ventilation0.90 [0.63-1.31]1.34 [0.97-1.85]1.01 [0.58-1.75]0.095
I vs overweightII vs overweightIII vs overweight
OutcomesaOR [LL-UL]aOR[LL-UL]aOR[LL-UL]P value
MACCE0.60 [0.34-1.08]0.72 [0.39-1.32]1.10 [0.62-1.95]0.016
Death during hospitalization0.63 [0.33-1.19]0.69 [0.35-1.35]1.23 [0.66-2.30]0.015
Respiratory failure1.04 [0.71-1.51]1.28 [0.88-1.88]1.40 [0.96-2.04]0.057
Mechanical ventilation0.99 [0.57-1.72]0.90 [0.51-1.59]1.33 [0.78-2.27]0.095

  • Citation: Srikanth S, Garg V, Subramanian L, Verma J, Sharma H, Klair HS, Kavathia SA, Teja JK, Vasireddy NS, Anmol K, Kolli D, Bodhankar SS, Hashmi S, Chauhan S, Desai R. In-hospital outcomes in COVID-19 patients with non-alcoholic fatty liver disease by severity of obesity: Insights from national inpatient sample 2020. World J Hepatol 2024; 16(6): 912-919
  • URL: https://www.wjgnet.com/1948-5182/full/v16/i6/912.htm
  • DOI: https://dx.doi.org/10.4254/wjh.v16.i6.912