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©The Author(s) 2024.
World J Hepatol. Feb 27, 2024; 16(2): 286-293
Published online Feb 27, 2024. doi: 10.4254/wjh.v16.i2.286
Published online Feb 27, 2024. doi: 10.4254/wjh.v16.i2.286
Blood test | Value | Unit |
Hematology | ||
WBC | 59.00 | × 102/μL |
RBC | 400.00 | × 104/μL |
Hb | 12.30 | g/dL |
Ht | 37.30 | % |
PLT | 13.30 | × 104/μL |
PT (%) | 81.90 | % |
Serum chemistry | ||
TP | 9.70 | g/dL |
ALB | 3.60 | g/dL |
T-Bil | 1.00 | mg/dL |
AST | 418.00 | U/L |
ALT | 366.00 | U/L |
ALP | 371.00 | U/L |
γ-GT | 102.00 | U/L |
LD | 388.00 | U/L |
BUN | 13.40 | mg/dL |
Cre | 0.65 | mg/dL |
CRP | 0.02 | mg/dL |
IgA | 605.00 | mg/dL |
IgM | 795.00 | mg/dL |
IgG | 3481.00 | mg/dL |
ANA | 80 | |
ASMA | 640 | |
AMA | < 20 | |
HAV-IgM | Negative | |
HEV-IgA | Negative | |
HBs-Ag | Negative | |
HBs-Ab | Negative | |
HBc-Ab | Positive | |
HBV-DNA | < 2.1 | Logcopy/mL |
HCV-Ab | Positive | |
HCV-RNA | < 1.2 | LogIU/mL |
CMV-IgM | Negative | |
CMV-IgG | Positive | |
VCA-IgM | Negative | |
VCA-IgG | Positive | |
EBNA | Positive | |
HLA | DR4 |
Blood test | ANA | ASMA |
Before DAAs (SOF/LDV) therapy | < 20 | < 20 |
After DAAs (SOF/LDV) therapy | 40 | 20 |
SVR 12 | 40 | 160 |
SVR 24 | 80 | 640 |
Ref. | Age | Sex | HLA-DR4 | Autoimmune disease | Genotype | DAA | Onset | Treatment | Follow up |
Matsumoto et al[29], 2018 | 81 | Female | Negative | None | 1 (serotype) | EBR/GZR | 2 months | PSL | Improvement |
Covini et al[31], 2018 | 72 | Female | NA | ITP | 1b | SOF/LDV | 2 wk | PSL | Improvement |
Montón et al[30], 2020 | 72 | Female | NA | None | 1b | SOF/LDV | 3 yr | PSL | Improvement |
Our case | 80 | Female | Positive | None | 1b | SOF/LDV | 9 months | PSL + UDCA | Development of PSC |
- Citation: Morihisa Y, Chung H, Towatari S, Yamashita D, Inokuma T. Autoimmune hepatitis and primary sclerosing cholangitis after direct-acting antiviral treatment for hepatitis C virus: A case report. World J Hepatol 2024; 16(2): 286-293
- URL: https://www.wjgnet.com/1948-5182/full/v16/i2/286.htm
- DOI: https://dx.doi.org/10.4254/wjh.v16.i2.286