Rifaximin discontinuation during broad-spectrum antibiotic treatment in critically ill patients with hepatic encephalopathy

Table 1 Grading of hepatic encephalopathy according to West Haven criteria and international society for hepatic encephalopathy and nitrogen metabolism criteria

West Haven criteria including minimal hepatic encephalopathy	International society for hepatic encephalopathy and nitrogen metabolism	Description
Minimal	Covert	Abnormal results of established psychometric or neuropsychological tests without clinical manifestations
Grade I		Despite oriented in time and space, the patient appears to have some cognitive/behavioral decay. Euphoria, anxiety, shortened attention span, slight mental slowing
Grade II	Overt	Disoriented for time. Lethargy, apathy, inappropriate behavior. Slight personality disorders
Grade III		Disoriented for time and space. Somnolence/semi-stupor. Responsive to stimuli. Bizarre behavior. Aggressive
Grade IV		Coma