Impact of utilization of hepatitis C positive organs in liver transplant: Analysis of united network for organ sharing database

Table 1 Demographics of different transplanted groups

	Mean age-donor (yr)	Mean age-recipient (yr)	Males (%)	BMI-recipient	Cold ischemia time	MELD
Group 1	42.72 ± 15.60	54.66 ± 11.63	62.87	29.1 ± 6.12	6.07 ± 2.23	25.22 ± 10.86
Group 2	42.96 ± 15.09	59.08 ± 6.82	75.92	28.67 ± 5.38	6.20 ± 2.46	19.41 ± 11.26
Group 3	40.00 ± 12.41	56.13 ± 10.9	66.8	28.92 ± 6.08	6.45 ± 2.03	21.74 ± 8.39
Group 4	37.71 ± 11.82	58.92 ± 6.76	76.53	28.92 ± 6.08	6.15 ± 2.51	18.24 ± 7.95

Group 1: Both donor and recipient negative for hepatitis C virus (HCV); Group 2: Negative donor and positive recipient for HCV; Group 3: Positive donor and negative recipient for HCV; and Group 4: Both positive donor and recipient for HCV. BMI: Body mass index; MELD: Model for end-stage liver disease.

Table 2 Cause of donor death and type of liver transplant in different groups

	Donor cause of death					Type of liver procedure
	Anoxia	Stroke	Head trauma	CNS tumor	Other	Whole	Partial	Split
Group 1	5832	5360	4844	64	336	16280	5	151
Group 2	2196	2007	1826	25	120	6121	2	51
Group 3	182	33	33	0	5	252	0	1
Group 4	1079	276	259	0	35	1648	1	0

Group 1: Both donor and recipient negative for hepatitis C virus (HCV); Group 2: Negative donor and positive recipient for HCV; Group 3: Positive donor and negative recipient for HCV; and Group 4: Both positive donor and recipient for HCV. CNS: Central nervous system; HCV: Hepatitis C virus.

Table 3 Diagnosis of transplant recipients at the time of listing

Primary diagnosis at listing	No. of patients	Percent
Alcoholic cirrhosis/acute alcoholic hepatitis	6434	26.25
Hepatitis C cirrhosis	5128	20.92
Non-alcoholic steatohepatitis cirrhosis	3764	15.36
Hepatoma	3010	12.28
Cryptogenic (idiopathic) cirrhosis	1082	4.41
Primary sclerosing cholangitis	941	3.84
Acute hepatic necrosis	696	2.84
Autoimmune cirrhosis	650	2.65
Primary biliary cirrhosis	582	2.37