Al Danaf L, Hussein Kamareddine M, Fayad E, Hussain A, Farhat S. Correlation between Fibroscan and laboratory tests in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis patients for assessing liver fibrosis. World J Hepatol 2022; 14(4): 744-753 [PMID: 35646268 DOI: 10.4254/wjh.v14.i4.744]
Corresponding Author of This Article
Said Farhat, MD, Associate Professor, Department of Gastroenterology, Saint George Hospital University Medical Center, El-achrafieh, Beirut 1100, Lebanon. saidfarhat@hotmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Clinical and Translational Research
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Apr 27, 2022; 14(4): 744-753 Published online Apr 27, 2022. doi: 10.4254/wjh.v14.i4.744
Table 1 Table summarizing the distribution of patients over fibrosis stages and their corresponding percentages
Stage of fibrosis
Number of patients (%)
F0
29 (40)
F0-F1
13 (18)
F2-F3
14 (19)
F3-F4
5 (7)
F4
12 (16)
Total
73 (100)
Table 2 Table summarizing distribution of fibrosis stages over two groups of ages
Patient’s age
Fibrosis stages
F0
F0-F1
F2-F3
F3-F4
F4
Total
20-49
17
7
7
0
2
33
> 50
12
6
7
5
10
40
Total
29
13
14
5
12
73
Table 3 Table summarizing the P value of the studied characteristics
Characteristic
P value
Age
0.0036
Gender
0.23
ALT
0.71
AST
0.07
Albumin
0.44
Cholesterol
0.22
GGT
0.22
LDL
0.07
HDL
0.68
ALP
0.033
Triglycerides
0.57
Bilirubin
0.0001
Glucose
0.0063
Platelet count
0.0001
PT INR
0.0011
PTT
0.0054
Table 4 Table showing differences in stiffness scores, aspartate transaminase/alanine transaminase ratio, aspartate transaminase platelet ratio index, and Fib-4 scores between patients with mild to moderate fibrosis and those with advanced fibrosis (expressed as mean ± SD)
< F2 (n = 42)
> F2 (n = 31)
P value
AST/ALT ratio
0.84 ± 0.47
1.31 ± 1.1
0.0029
APRI score
0.35 ± 0.26
1.08 ± 1.2
3.59 × 10-7
Fib-4 score
1.07 ± 0.73
3.41 ± 3.44
9.11 × 10-9
Citation: Al Danaf L, Hussein Kamareddine M, Fayad E, Hussain A, Farhat S. Correlation between Fibroscan and laboratory tests in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis patients for assessing liver fibrosis. World J Hepatol 2022; 14(4): 744-753