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Copyright ©The Author(s) 2021.
World J Hepatol. Nov 27, 2021; 13(11): 1699-1706
Published online Nov 27, 2021. doi: 10.4254/wjh.v13.i11.1699
Table 1 Hepatopulmonary syndrome definition
Index

OxygenationPaO2 < 80 mmHg or A-a gradient (corrected for age) > 15 mmHg or 20 mmHg if age > 64 years while breathing room air
Intrapulmonary vasodilationConfirmed by contrast-enhance echocardiography or lung perfusion scanning showing brain shunt fraction > 6%
Liver diseaseCirrhosis and/or portal hypertension
Table 2 Staging based on severity of hepatopulmonary syndrome
Stage
Partial pressure of oxygen (mmHg) on room air
Mild≥ 80
Moderate≥ 60 to < 80
Severe≥ 50 to < 60
Very severe< 50 on room air or < 300 while breathing 100% oxygen