Minireviews
Copyright ©The Author(s) 2018.
World J Hepatol. Jul 27, 2018; 10(7): 479-484
Published online Jul 27, 2018. doi: 10.4254/wjh.v10.i7.479
Table 1 Summary of previous reports of repeat laparoscopic liver resection
nDiseasePrevious LR(open:lap)ProcedureBleeding(mL)Operating time (min)Conversion(n)Postoperative hospital stay (d)MorbidityMortalityRef.
12HCC4:8LLS (n = 5), Pt (n = 4), Seg (n = 3)297 ± 134 272.2 ± 120114.4 ± 11.0 63.9 ± 13.317.4 ± 2.5 6.2 ± 3.026.60%0%[20]
2MetNDNDNDNDNDNDNDND[21]
6HCC3:3 (Lap RFA, n = 2)LLS (n = 2), Pt (n = 4)283.3 ± 256.3140.8 ± 35.705.67 ± 1.6316.7%0%[24]
76Met (n = 63), HCC (n = 3), others (n = 10)28:44LLS (n = 4), Pt, seg (n = 53), above-seg (n = 19)300 (0–5000)180 (80–570)86 (2–42)26%0%[23]
4HCC (n = 3), Met (n =1)0:4LLS (n = 1), Pt (n = 3)481.7 ± 449.5312.3 ± 158.4110.6 ± 7.423.4%0%[22]
3HCC0:3ND281.3 (mean)264.6 (mean)08.6 (mean)0%[26]
17NDNDNDNDNDNDNDNDND[25]
20HCC15:5Pt78 (1–1500)239 (69–658)2 (HALS)9 (5–22)5%0%[27]
20HCC (n = 2), Met (n = 16), others (n = 2)0:20Minor (n = 14), major (n = 6)400 (IQR 150-200 mL)285 (IQR 195-360)34 (1-57)10%0%[30]
12HCC (n = 8), Met (n = 2), others (n = 2)8:4Pt (n = 9), Subseg (n = 3)50 (NC–840)301 (104–570)012 (9–30)0%0%[29]
11HCC6:5LLS = 2 Subseg = 9100 (50-500)200 (131-352)06 (3-17)18.2%0%[33]
27MetNDMajor = 25 Minor = 2ND (4 patients received transfusion)252.5 (180-300)19 (IQR 8-18)48.1%0%[32]
8HCC6:2Sec = 2 Seg = 2 Subseg = 4200 (30-5000)343 (120-530)13.5 (3-8)12.5%0%[31]
20HCC (n = 15) Met (n = 5)12:8Anatomical = 1 Non-anatomical = 19159 +/- 256225 +/- 85114.2 +/- 5.40%0%[19]
33HCC and combined (n = 18) Met (n = 15)21:12Anatomical = 11 Non-anatomical = 2230 (NC-1012)217 (43-356)06.5 (3-47)6.1%3%[18]
Table 2 The summary of present status and future perspectives of repeat laparoscopic liver resection
Present status
There are 16 reports of small series. Controversy still exists in the indication of repeat LLR
These studies generally reported that it has better short-term outcomes without compromising the long-term outcomes (similar or longer operation time, reduces bleedings, reduced blood transfusion rate, less or similar morbidity and shorter hospital stay)
It facilitates more meticulous dissection of adhesions strained by the pneumoperitoneum using magnified laparoscopic view
Complete adhesiolysis can be avoided when the adhesion does not affect the current operative procedure
Operation time was shorter and the adhesiolysis was easier for the patients previously treated with LLR than open LR
It requires smaller (than open) working space between adhesions (this fact allows for minimal adhesiolysis, and operation time and bleeding amount were similar in primary and repeat LLR, although those from open LR are longer and increased)
Future perspectives
Further evaluations of anatomical resection or resections exposing major vessels after previous anatomical resection are needed
One of the possible advantages for minor repeat LR of CLD liver is that the deterioration of liver function can be minimized
It could prolong the overall survival of the HCC patients with CLD as a powerful local therapy which can be applied repeatedly with minimal deterioration of liver function