Multipotent stromal cells stimulate liver regeneration by influencing the macrophage polarization in rat

doi:10.4254/wjh.v10.i2.287

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Feb 27, 2018 (publication date) through Jan 2, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Feb 27, 2018; 10(2): 287-296
Published online Feb 27, 2018. doi: 10.4254/wjh.v10.i2.287

Table 1 Oligonucleotide sequences

Target designation	5'-end primer	3'-end primer
Il1β	CTGTCTGACCCATGTGAGCT	ACTCCACTTTGGTCTTGACTT
Il6	TACATATGTTCTCAGGGA GAT	GGTAGAAACGGAACTCCAG
Il10	GCCCAGAAATCAAGGAGCAT	TGAGTGTCACGTAGGCTT CTA
Tnfα	CCACCACGCTCTTCTGTCTA	GCTACGGGCTTGTCACTCG
Hgf	GGCCATGGTGCTACACTCTT	TTGTGGGGGTACTGCGAATC
Tgfβ1	CCGCAACAACGCAATCTATG	AGCCCTGTATTCCGTCTCCTT
Actβ	GAGATTACTGCCCTGGCTCC	GCTCAGTAACAGTCCGCCTA
B₂m	CTCGCTCGGTGACCGTGAT	GGACAGATCTGACATCTCGA
Gapdh	GCGAGATCCCGCTAACATCA	CCCTTCCACGATGCCAAAGT

Table 2 Liver-to-body weight ratio dynamics (Mean ± SD, %)

Time after operation, d	Multipotent stromal cells transplantation group	Comparison group
Intact controls	4.5 ± 0.9
3	1.8 ± 0.3	1.4 ± 0.1^a
7	2.4 ± 0.7	2.7 ± 0.3^a
10	3.1 ± 0.2	2.6 ± 0.2^a

^aP > 0.05.

Citation: Elchaninov A, Fatkhudinov T, Usman N, Arutyunyan I, Makarov A, Lokhonina A, Eremina I, Surovtsev V, Goldshtein D, Bolshakova G, Glinkina V, Sukhikh G. Multipotent stromal cells stimulate liver regeneration by influencing the macrophage polarization in rat. World J Hepatol 2018; 10(2): 287-296
URL: https://www.wjgnet.com/1948-5182/full/v10/i2/287.htm
DOI: https://dx.doi.org/10.4254/wjh.v10.i2.287