Rising incidence, progression and changing patterns of liver disease in Wales 1999-2019
Thomas Peter Ignatius Pembroke, Andrew Godkin, Department of Gastroenterology and Hepatology, University Hospital of Wales, Cardiff CF14 4XN, United Kingdom
Thomas Peter Ignatius Pembroke, Andrew Godkin, Division of Infection and Immunity, Cardiff University, Cardiff CF14 4XW, United Kingdom
Gareth John, Berry Puyk, Keith Howkins, Ruth Clarke, Digital Health and Care Wales, NHS Wales, Cardiff CF11 9AD, United Kingdom
Fidan Yousuf, Marek Czajkowski, Andrew Yeoman, Gwent Liver Unit, Royal Gwent Hospital, Newport NP20 2UB, United Kingdom
Jane Salmon, Public Health Wales, NHS Wales, Cardiff CF10 4BZ, United Kingdom
Author contributions: Pembroke TPI, John G, Salmon J, and Yeoman A developed the concept and design of the study; Yousuf F, Czajkowski M and Yeoman A collected data; Pembroke TPI, John G, Puyk B, Howkins K, Clarke R and Yeoman A analysed the data; Pembroke TPI, Godkin A, Salmon J, and Yeoman A prepared the manuscript.
Institutional review board statement: This study was initiated as a dedicated workstream of the Liver Disease Implementation Group and Public Health Wales to establish a Liver Registry for Wales as a core workstream for this project. This manuscript represents the report of this commissioned work. As such it not been reviewed by the university review board.
Informed consent statement: This study was conducted in keeping with the Helsinki declaration. The design of this study was discussed with the South Wales research ethics committee and was not classed as research requiring regulatory approvals by Health Research Authority, United Kingdom.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Thomas Peter Ignatius Pembroke, FRCP, MBBS, PhD, Doctor, Senior Lecturer, Department of Gastroenterology and Hepatology, University Hospital of Wales, Heath Park, Cardiff CF14 4XN, United Kingdom. firstname.lastname@example.org
Received: August 25, 2022
Peer-review started: August 29, 2022
First decision: October 17, 2022
Revised: November 17, 2022
Accepted: December 31, 2022
Article in press: December 31, 2022
Published online: January 27, 2023