Monoclonal antibodies: Principles and applications of immmunodiagnosis and immunotherapy for hepatitis C virus

doi:10.4254/wjh.v7.i22.2369

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Oct 8, 2015 (publication date) through May 6, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Oct 8, 2015; 7(22): 2369-2383
Published online Oct 8, 2015. doi: 10.4254/wjh.v7.i22.2369

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Figure 1 Diagrammatic procedure of the production of mouse monoclonal antibodies by hybridoma technology. ELISA: Enzyme-linked immunosorbent assay; PEG: Polyethylene glycol; DMSO: Dimethyl sulfoxide; HAT: Hypoxanthine-aminopterin-thymidine; HT: Hypoxanthine thymidine.

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Figure 2 Diagrammatic presentations showing the applications of mouse and human monoclonal antibodies and their methods of production. EBV: Epstein-Barr virus.

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Figure 3 Generation of fully human monoclonal antibodies by Epstein-Barr virus immortalization. EBV: Epstein-Barr virus; HCV: Hepatitis C virus; IL2: Interleukin-2; ELISA: Enzyme-linked immunosorbent assay.

Citation: Tabll A, Abbas AT, El-Kafrawy S, Wahid A. Monoclonal antibodies: Principles and applications of immmunodiagnosis and immunotherapy for hepatitis C virus. World J Hepatol 2015; 7(22): 2369-2383
URL: https://www.wjgnet.com/1948-5182/full/v7/i22/2369.htm
DOI: https://dx.doi.org/10.4254/wjh.v7.i22.2369