Genetic susceptibility to autoimmune liver disease

doi:10.4254/wjh.v3.i1.1

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Jan 27, 2011 (publication date) through Feb 5, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jan 27, 2011; 3(1): 1-7
Published online Jan 27, 2011. doi: 10.4254/wjh.v3.i1.1

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Figure 1 Regulation of T cell activation by cytotoxic T lymphocyte antigen 4. While cytotoxic T lymphocyte antigen 4 (CTLA-4) is constitutively expressed on regulatory T cells (Tregs), its expression is induced on effector T cells (Teff) upon activation. While it is well-established that CTLA-4 is required for the optimal function of Tregs, its role on natural killer T cells or effector T cells is less clear. DCs: dentritic cells; NKT: natural killer T; GSLs: glycosphingolipids.

Citation: Mattner J. Genetic susceptibility to autoimmune liver disease. World J Hepatol 2011; 3(1): 1-7
URL: https://www.wjgnet.com/1948-5182/full/v3/i1/1.htm
DOI: https://dx.doi.org/10.4254/wjh.v3.i1.1