Role of mac-2 binding protein glycosylation isomer in predicting fibrosis in patients with metabolic dysfunction-associated steatotic liver disease

Figure 1 Study flow diagram. CBC: Complete blood count; FIB-4: Fibrosis-4 Index; HbA1c: Hemoglobin A1c; M2BPGi: Mac-2 binding protein glycosylated isomer; MRE: Magnetic resonance elastography.

Figure 2 Median of mac-2 binding protein glycosylated isomer levels. A: Median of mac-2 binding protein glycosylated isomer (M2BPGi) levels between different fibrosis stages; B: M2BPGi distributed in various sex-subgrouped fibrosis stages; C: M2BPGi distribution through diabetes-subgroups fibrosis stages. COI: Cut-off index; M2BPGi: Mac-2 binding protein glycosylated isomer. ^aKruskal-Wallis test, Dunn's test for post-hoc analysis. ^bTwo-way analysis of variance, Sidak's test for multiple comparison, P < 0.05.

Figure 3 Correlation between mac-2 binding protein glycosylated isomer and major markers of liver fibrosis. A: The correlation with FibroScan; B: The correlation found between mac-2 binding protein glycosylated isomer (M2BPGi) and the Fibrosis-4 Index score; C: The correlation between M2BPGi and magnetic resonance elastography. COI: Cut-off index; FIB-4: Fibrosis-4 Index; M2BPGi: Mac-2 binding protein glycosylated isomer; MRE: Magnetic resonance elastography.