Copyright
©The Author(s) 2023.
World J Hepatol. Jun 27, 2023; 15(6): 775-785
Published online Jun 27, 2023. doi: 10.4254/wjh.v15.i6.775
Published online Jun 27, 2023. doi: 10.4254/wjh.v15.i6.775
Figure 1 Tumor budding in primary liver cancers.
A: Tumor budding consisting of small clusters of 4 or fewer tumor cells present at the invasive edge in a case of hepatocellular carcinoma; B: The main processes and mechanisms involved in tumor budding. EMT: Epithelial to mesenchymal transition; EpCAM: Epithelial cell adhesion molecule; CAFs: Cancer-associated fibroblasts; MMP: Matrix metalloproteinase; TRKB: Tyrosine kinase receptor B; u-PA: Urokinase plasminogen activator.
- Citation: Unal B, Celik MY, Gedik EO, Bassorgun CI, Elpek GO. Tumor budding as a potential prognostic marker in determining the behavior of primary liver cancers. World J Hepatol 2023; 15(6): 775-785
- URL: https://www.wjgnet.com/1948-5182/full/v15/i6/775.htm
- DOI: https://dx.doi.org/10.4254/wjh.v15.i6.775