Prevalence of nonalcoholic fatty liver disease and its association with age in patients with type 2 diabetes mellitus

Figure 1 The participants in the present study consisted of 724 Japanese type 2 diabetic patients who consulted at Meijo Hospital from April 2019 to September 2020. We excluded participants who had chronic hepatitis B (n = 6) and C (n = 28) infection, no assessment of hepatitis B surface antigen (HBsAg) and hepatitis C virus antibody (n = 105), and alcohol intake ≥ 20 g/d (n = 33). We also excluded 115 participants with no abdominal computed tomography examinations. The final analysis included 437 participants (269 men and 168 women). HCVAb: Hepatitis C virus antibody; HBsAg: Hepatitis B surface antigen; CT: Computed tomography.

Figure 2 The patients were stratified according to age, hemoglobin level, and high-density lipoprotein cholesterol level, and the association with fatty liver was assessed. A: The prevalence of fatty liver significantly decreased with age (P < 0.001); B: The prevalence of fatty liver significantly increased as hemoglobin increased (P < 0.001); C: The prevalence of fatty liver was significantly higher in patients with high-density lipoprotein cholesterol of < 70 mg/dL (29.9%) than those with HDL cholesterol ≥ 70 mg/dL (13.8%) (P = 0.012). HDL: High-density lipoprotein